DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRAT and cratb

DIOPT Version :9

Sequence 1:	NP_001287195.1	Gene:	CRAT / 40787	FlyBaseID:	FBgn0037440	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001004594.2	Gene:	cratb / 447855	ZFINID:	ZDB-GENE-040912-162	Length:	614	Species:	Danio rerio

Alignment Length:	617	Identity:	210/617 - (34%)
Similarity:	347/617 - (56%)	Gaps:	26/617 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 KVLPASSYSTVQKTIPLEQP-NLLKYH-VLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEF--L 113
            |.:||...|:......|.|. :.:.|. |.||.:||.|::..:||||..:|.:..:.|..||  .
Zfish     4 KRIPARLCSSFMMRAVLRQAHSSVPYQPVPPLGQTLQRYLAALEPLLPEDELEHTRRIVQEFGCA 68

  Fly   114 KKQGRELQLLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTAR 178
            ...|..||..|.:......||::..|::.|||..|.|:.|..:|.::.||::|.|.|..:.:.::
Zfish    69 GGLGESLQRELIKRAKHSHNWISDWWVQWAYLECRQPLAVHSNPAISLPKRDFTDWRGQLVFASK 133

  Fly   179 VIYGLGEFNDMVHANKIPIVKMGKNELDNSQFGKVFGTCRIPRRGTDEIVY----NPDSDYVVVI 239
            :|.|:..|...|.:.::.|..|..|.|....|.|:|.:||||....|.:|:    .....::.|:
Zfish   134 LIAGVLNFKAEVDSGRLAIEYMRGNPLCMELFPKLFSSCRIPGPKHDLVVHYGRPRRGPAHITVV 198

  Fly   240 YKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKETQVG-VPYGILTTDSRDNWAEAYEYLVETPG 303
            ....|:||.:|:.:|..:....:.|||..|..:..:.. .|.||||::.|..|.:||..|:....
Zfish   199 RNYQFFQLDVYNSDGTPLTESQIHAQLLRIRSQSWKTDKEPMGILTSEHRHTWGQAYTRLLRDKI 263

  Fly   304 NRDALKTIQGALFTVSLDEGTILKEGEE--TDELILSLIHGSGSKINSGNRWMDKTIQLVVNPNG 366
            |:::::.|:.:|||:.|| ..:::..:|  :..:...::||.|:..||||||.|||:|.||..:|
Zfish   264 NKESVRLIEKSLFTLCLD-SPVMRISDENYSSRMAAQILHGGGTYSNSGNRWFDKTLQFVVGEDG 327

  Fly   367 NVGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSFGQSGSQDFAP------AQKIQFSSSNKSLEKS 425
            :.|..|||:.|||.|||.::|:|::..|...|..       ||      .:|:.| ..|..::..
Zfish   328 SWGLLYEHATAEGPPIATLLDHVLEYCKMTDSVR-------APLIPLPMPKKLYF-YINSEIKWD 384

  Fly   426 LNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHL 490
            |.:|::|:|.|.:.|.:|...|..|||.|:|:.:|.|:||||:|:|||:|::|:|..|..:.|.|
Zfish   385 LEMAKQNLDILINDLDIKCFNFQCFGKKFVKQLKLSPNSFVQLAIQLAYYRVHNEVCAACDIASL 449

  Fly   491 RIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLG 555
            |:|.||||:.|||.:|:.|:|.:|..|..|:.:.:...|||||.::....:.:|.|:|:||||||
Zfish   450 RMFRGGRTDYIRSPTNQMLSFIQAFDDVAVSREAKIQLLREAVNAYSLLTEQSLMGQGIDRHLLG 514

  Fly   556 LKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFMGYGPATDDGYACCYNPRDNDIIL 620
            |||.|:|:...:|..|....:..::|:::.|.||.|..|:.|.:||...||||.||||:.:.:..
Zfish   515 LKLQAIENGLSVPRIFMDTAYGLATHWKLRTGQVPTNTDSVMCFGPLVPDGYAVCYNPQQDHLHF 579

  Fly   621 AISAWRHCPITDHLKFVKTLEQSFFEMKNVLE 652
            :::|:..|..|:..|...|||:|..:::.:.:
Zfish   580 SVTAFNCCEDTNAEKLALTLERSLRDVQELFQ 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	204/589 (35%)
cratb	NP_001004594.2	Carn_acyltransf	28..607	CDD:279140	204/587 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594977
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1807
OMA	1	1.010	-	-		QHG59015
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	O	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910