DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRAT and CROT

DIOPT Version :9

Sequence 1:	NP_001287195.1	Gene:	CRAT / 40787	FlyBaseID:	FBgn0037440	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001334704.1	Gene:	CROT / 43332	FlyBaseID:	FBgn0039543	Length:	618	Species:	Drosophila melanogaster

Alignment Length:	607	Identity:	159/607 - (26%)
Similarity:	278/607 - (45%)	Gaps:	42/607 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LPLEE---TLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETGSKEKNWLAHRWLK 141
            |||.|   |:.|:.:.::|..|.||..:.:....||....|.:|...|::..:..:|||...|..
  Fly    26 LPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRAAGMRNWLGTWWED 90

  Fly   142 AAYLTYRDPVTVFVSPGMTFPKQ----NFRDSRAF-VDYTARVIYGLGEFNDMVHANKIPIVKM- 200
            ..|...|.|:..:..  |..|.|    ...::..: :...||.|:...||.|:...:.|..:..
  Fly    91 YGYHLIRMPLLPYQL--MVMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLTRKSSIKPLSSN 153

  Fly   201 -GKNELDNSQFGKVFGTCRIPRRGTDEIVYN-------PDSDYVVVIYKNHFYQLKIYSKEGKLI 257
             ||.:..::.:...|.|||:|....|.|..:       ....::::..|...:......::..::
  Fly   154 GGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIFDCVHEDDTIL 218

  Fly   258 AAPCLAAQLENI--VLKETQVGVPYGILTTDSRDNWAEAYEYLVE-TPGNRDALKTIQGALFTVS 319
            :||.:...|:.:  :|....:|.....|:.|.|..||.....|.| :..|::.|..::.|...:.
  Fly   219 SAPEILVALQRVRSILDYEPLGDCVPTLSHDERSTWARNRNRLREISVANKETLLLVESACMEIC 283

  Fly   320 LDEGTILKEGEETDEL-ILSLIHGSGSKINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIA 383
            ..|.: .|:.||:.:| :...:|         :||.|::..::...||...:|.|||..:|....
  Fly   284 WYEQS-PKDYEESCQLGLYGDLH---------SRWADRSSSIIAFRNGRCNWTGEHSCYDGTVSI 338

  Fly   384 MMMDYVVQKMKE--DPSFGQSGSQDFAPAQKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLK 446
            ....::.....|  :|.:.::...:....:::.|...: :|:..:...|:::|.....:.:....
  Fly   339 SYATFMQLSFLEVPEPDWAEAEKGNVLEVKELHFQLDD-TLKNEIKRVQKDIDDRGIDVTVTFTA 402

  Fly   447 FNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAF 511
            |:.:||||:|..||.||||||:.:|.|:|:||.|....||:|.:|.:..|||||:|||::....|
  Fly   403 FDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETALMRQYYNGRTETLRSCTSAVAEF 467

  Fly   512 SRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGF 576
            .||..:..|.|...|...|.||..|:.:...|.:|.|:||||.||...|.|....||.|:..|.:
  Fly   468 LRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRHLFGLWCAAYESKMDIPAFYDDPMY 532

  Fly   577 VKS---SHFRMSTSQVATKYDAFMGY-GPATDDGYACCYNPRDNDIILAISAWRHCPITDHLKFV 637
            .||   .:|.:|:|.:.  :.|.:|: .|...|||...|:.....:.:..:|:|....|...||.
  Fly   533 TKSGGGGNFVLSSSTLG--FTANVGFVAPMVFDGYGVFYSITSEAVFINTTAYRDSLKTSARKFN 595

  Fly   638 KTLEQSFFEMKNVLEKNPPETK 659
            ...:.||..:..:||:...|:|
  Fly   596 DIFKDSFRRISVLLEQLAKESK 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	155/594 (26%)
CROT	NP_001334704.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469042
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950