Protein Alignment CRAT and ChAT

DIOPT Version :9

• Sequence 1: NP_001287195.1
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 712
• Identity: 223/712 - (31%)
• Similarity: 350/712 - (49%)
• Gaps: 95/712 - (13%)

  Fly    12 PTS-ERILEKTEAEMKFRGNGKLLWNLTKNSLA-QQSPNGIAKKVLPASSYSTVQKTIPLEQPNL 74
            |.| :|::......:..|     |.|:|.:... :.|...|.||.|     ||.:.......|:.
  Fly    33 PNSPQRVVSNLRGFLTHR-----LSNITPSDTGWKDSILSIPKKWL-----STAESVDEFGFPDT 87

  Fly    75 L-KYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQG---RELQLLLEETGSKEKNWL 135
            | |..|..|:||:..::..:||:.||.:.:|.|.:..:|...||   |..|.||::. ..|.||.
  Fly    88 LPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLHQYLLDKR-EAEDNWA 151

  Fly   136 AHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTARVIYGLGEFNDMVHANKIPIVKM 200
            .:.||...|:..|.|:.:..:|||.||.:.|:.......:.||::.|:....:|:.:.::|:.:.
  Fly   152 YYYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERA 216

  Fly   201 GKNE----LDNSQFGKVFGTCRIPRRGTDEIV------YNPDSDYVVVIYKNHFYQLKIY-SKEG 254
            ...|    |..:|:.::.|:||.|....|...      .|.:..:||||.:|..|.:.:. |..|
  Fly   217 ASREKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQASDRG 281

  Fly   255 KL----IA---------APCLAAQLENIVLKETQVGVPYGILTTDSRDNWAEAYEYLVETPGNRD 306
            ||    ||         ||||.|:           .||.|:||.:.|..||...|.|.|...|:.
  Fly   282 KLSESEIASQILYVLSDAPCLPAK-----------PVPVGLLTAEPRSTWARDREMLQEDERNQR 335

  Fly   307 ALKTIQGALFTVSLDE---------------GTILKEGEETDELILS--LIHGSGSKINSGNRWM 354
            .|:.|:.|...:.|||               .|:.:.|:. ||..::  :|||.||:.||||||.
  Fly   336 NLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDR-DETNMAHEMIHGGGSEYNSGNRWF 399

  Fly   355 DKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSFGQSGSQ-DFAPAQKIQFSSS 418
            |||:||::..:|..|..||||.:||..:..:::.:.:|::|.|.......| ...|.::::: ..
  Fly   400 DKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHPDEDNGLPQHHLPPPERLEW-HV 463

  Fly   419 NKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPA 483
            ...|:.....|.::|||..|.|...|.::..:||.|||..::.||.::|:|||||.||::....|
  Fly   464 GPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVA 528

  Fly   484 QYESAHLRIFDGGRTETIRSCSNESLAFSRAM---QDPNV------TDQERAAK----------L 529
            .||||..|.|..||.:.||:.|.|:|.:::||   :..||      .|:|.:.|          |
  Fly   529 TYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHL 593

  Fly   530 RE---AVVSHQTYAKLA-LQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVA 590
            ||   ..|:.||...:. :.|.|:|..||||:..::|.:..:.|.||...::.|..|.:||||||
  Fly   594 RELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQVA 658

  Fly   591 TKYDAFMGYGPATDDGYACCYNPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEMKNVLE 652
            ...|:||||||.|..||.|.|||....|:..:||:..|..|...::.|:|:.|...|:::|:
  Fly   659 CSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLLQ 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	206/642 (32%)
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	206/641 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469037
Domainoid	1	1.000	234	1.000	Domainoid score	I397
eggNOG	1	0.900	-	-		E1_KOG3717
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I707
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D15298at7147
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2058
SonicParanoid	1	1.000	-	-		X630
	11	10.930