DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRAT and CG5122

DIOPT Version :9

Sequence 1:	NP_001287195.1	Gene:	CRAT / 40787	FlyBaseID:	FBgn0037440	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster

Alignment Length:	659	Identity:	290/659 - (44%)
Similarity:	419/659 - (63%)	Gaps:	29/659 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SPTSERILEKTEAEMKF-----------RGNGKLLWNLTKNSLAQQSPNGIAKKVLPAS-SYSTV 63
            ||:::.|...|..::|.           |.|.::     |...|:: |..:.||.:.:. .:...
  Fly   596 SPSNKEIKIATVEKIKSPKPLSKPQYSKRSNCEV-----KTQCAEK-PQKVPKKCIKSEIRHLAD 654

  Fly    64 QKTIPLEQPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETG 128
            ....|.::|.|.|:..|||::::..:::::||.|..||.:.::.:..:|:..:|.:||.||||..
  Fly   655 ANNDPNKKPELKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKLQQLLEEEA 719

  Fly   129 SKEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTARVIYGLGEFNDMVHAN 193
            ....|||..||.::|||||:.|:|||.|||::||.|.|:|:..|:::||:.|||:.||..:|..|
  Fly   720 EGTDNWLTPRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFLNFTAKAIYGMCEFKQLVDQN 784

  Fly   194 KIPIVKMGKNELDNSQFGKVFGTCRIPRRGTDEIVYNPDSDYVVVIYKNHFYQLKIYSKEGKLIA 258
            |||:|:|||::||||||||:|||.|.|.|..|.|....|:||:||:|.|::::|.|||:.|.|:.
  Fly   785 KIPVVQMGKHQLDNSQFGKIFGTVRKPGRFCDTIEQYNDADYIVVVYNNNYFKLPIYSQSGALLH 849

  Fly   259 APCLAAQLENIVLKETQVGVPYGILTTDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEG 323
            |..|...|::|:....:||..:|:||.|:|.||||||..|....||.|.::||:.:||.|.||..
  Fly   850 AHTLRDALQDILECPIKVGKHFGLLTHDNRSNWAEAYTVLCRPHGNADTVETIEQSLFVVCLDNC 914

  Fly   324 TILKEGEETDELILSLIHGSGSKINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDY 388
            ....:|||.......|:||.|.:.||.||||||||||:|||||..||.||||||:.||:||:||:
  Fly   915 VPTPKGEERIVQAHQLLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAMLMDF 979

  Fly   389 VVQKMKEDPSFGQSGSQDFAPAQK------IQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKF 447
            |..|:.| |::|..|.:    |.|      ::|...|:.:...|..|:.|:.::...|||.|:.|
  Fly   980 VQLKVTE-PNYGCEGCE----ADKKVTSNLLKFQPVNECINLWLCQARRNIQRIVSQLQMNVINF 1039

  Fly   448 NGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFS 512
            ..:||.|||.|.|.|||::||||.||:|.|:.:.||||||||||||..||||||||.||||..|.
  Fly  1040 ECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESKTFL 1104

  Fly   513 RAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFV 577
            .|||....:..|:.|.|::||.:|:...|.|:.|:|:||||.||:.||||...||||||:|.|:|
  Fly  1105 LAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYV 1169

  Fly   578 KSSHFRMSTSQVATKYDAFMGYGPATDDGYACCYNPRDNDIILAISAWRHCPITDHLKFVKTLEQ 642
            :|..|::.||||||..:.||.|||...|||..||||:::.|..|||||:.|...:.::|.|.:::
  Fly  1170 RSVTFQLFTSQVATSNEGFMAYGPLLSDGYGVCYNPKESKITFAISAWKSCKEINTIRFAKAIKK 1234

  Fly   643 SFFEMKNVL 651
            |..:|:.::
  Fly  1235 SLNDMRKLI 1243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	275/579 (47%)
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	275/579 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469034
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	1	0.900	-	-		E1_KOG3717
Homologene	1	1.000	-	-		H598
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D15298at7147
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
	11	10.750