Protein Alignment CRAT and Cpt1c

DIOPT Version :10

• Sequence 1: NP_649650.2
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_006229128.1
• Gene: Cpt1c / 308579
• RGDID: 1305384
• Length: 802
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 184/664 - (27%)
• Similarity: 305/664 - (45%)
• Gaps: 97/664 - (14%)

  Fly    47 PNGIAKKVLPASSYSTVQKTIPLEQPNLLKY-HVLP------LEETLNRFMTTVEPLLTPEEFQR 104
            |:|....  |..::..:.:......|.|..: ..||      .:||:.:::.::.|:|..:.|..
  Rat   139 PHGTMSS--PTKTWLALVRIFSGRHPRLFSFQRALPRQPVPGAQETVRKYLESMRPVLRDDAFDS 201

  Fly   105 QKGITSEFLKKQGRELQLLLEETGSKEKNWLAHRWLKAAYLTYRDPVT----------VFVSPGM 159
            ...:.::||:.|...|||.|:.......|:::..|.:..||..|..:.          ::|:|
  Rat   202 VVALANDFLRLQAPRLQLYLQLKSWCASNYVSDWWEEFVYLRSRGSLVNSTYYMMQDFLYVTP-- 264

  Fly   160 TFPKQNFRDSRAFVDYTARVIYGLGEFNDMVHANKI-PIVKMGKNELDNSQFGKVFGTCRIPRRG 223
             .|.|..|...|        ::.|..:..:::..:| |.:.||...|.::|:.::|.|.|||...
  Rat   265 -TPLQAARAGNA--------VHTLLLYRHLLNRQEIPPTLLMGMRPLCSAQYERMFNTTRIPGVE 320

  Fly   224 TDEIVYNPDSDYVVVIYKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKETQVGVP----YGILT 284
            .|.:.:..||.:|.|.::..|:::..:|..|.|  :|....|....:|.:.....|    ...||
  Rat   321 KDYLCHLQDSQHVAVFHQGRFFRVGTHSSNGLL--SPRALEQQFQYILDDPSPACPLEEHLAALT 383

  Fly   285 TDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDE--GTILKE--GEETDELILSLIHGSGS 345
            ...|..||:..| .|:|.. ..||:|::||.|.||||.  ..:.:|  ....|....:|:.|.|.
  Rat   384 AAPRSMWAQVRE-SVKTHA-ATALETVEGAAFFVSLDSEPAGLTRENPAASLDTYAHTLLTGQGH 446

  Fly   346 KINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIA------------MMMDYVVQ---KMKE 395
                 :||.||:..|:|..||.:|.:.|||.|: .|:|            ..:.|...   |...
  Rat   447 -----DRWFDKSFTLIVFSNGKLGLSVEHSWAD-CPVAGHLWEFTLATECFQLGYATDGHCKGHP 505

  Fly   396 DPSFGQSGSQDFAPAQKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRL 460
            ||:..:        .|::|:... |.::.|:::|......|:..:...|..|..|||.|||...:
  Rat   506 DPALPK--------PQRLQWDLP-KQIQPSISLALRGAKTLSGNIDCHVFPFFHFGKSFIKGCHV 561

  Fly   461 GPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQER 525
            ..|||:|:.||||.::...:....||||..|:|..|||||:|||:.|:..|.|||::...|||:.
  Rat   562 SSDSFIQLVLQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMENKERTDQQC 626

  Fly   526 AAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMA-LEHSKPIPEFFKSPGF--VKSSHFRMSTS 587
            .|..||||..||...|.|:.|:|:||||..|.:|: |.|       .:||..  |:|..:.:|||
  Rat   627 LALFREAVDKHQALLKAAMSGQGIDRHLFALYIMSRLLH-------MQSPFLTQVQSQQWLLSTS 684

  Fly   588 QVATK---------YDAFM----GYGPATDDGYACCY-NPRDNDIILAISAWRHCPITDHLKFVK 638
            |:..:         |..::    |:|||.|.||...| ...:|.|...||:.:....||..:..:
  Rat   685 QIPVQQTHLFDVHNYPDYVSSGGGFGPAHDHGYGVSYIFMGENAISFHISSKQSSTETDSHRLGQ 749

  Fly   639 TLEQSFFEMKNVLE 652
            .:|.:..::.::.:
  Rat   750 HIEDALLDVASLFQ 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_649650.2	Carn_acyltransf	79..642	CDD:459926	178/619 (29%)
Cpt1c	XP_006229128.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..753	CDD:459926	176/615 (29%)