Protein Alignment CRAT and Cpt1a

DIOPT Version :9

• Sequence 1: NP_001287195.1
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_113747.2
• Gene: Cpt1a / 25757
• RGDID: 2396
• Length: 773
• Species: Rattus norvegicus
• Alignment Length: 623
• Identity: 176/623 - (28%)
• Similarity: 297/623 - (47%)
• Gaps: 75/623 - (12%)

  Fly    71 QPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETGSKEKNWL 135
            |.:|.:..|..:::|::|::.:|.||:..|:|||...:..:|....|.:||..|:.......|::
  Rat   168 QTSLPRLPVPAVKDTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYV 232

  Fly   136 AHRWLKAAYLTYRDPVTV----------FVSPGMTFPKQNFRDSRAFVDYTARVIYGLGEFNDMV 190
            :..|.:..||..|.|:.|          :::|      .:.:.:||     ...|:.:..:...:
  Rat   233 SDWWEEYIYLRGRGPLMVNSNYYAMEMLYITP------THIQAARA-----GNTIHAILLYRRTL 286

  Fly   191 HANKI-PIVKMGKN-ELDNSQFGKVFGTCRIPRRGTDEIVYNPDSDYVVVIYKNHFYQLKIYSKE 253
            ...:: ||..:|.. .|.::|:.::|.|.|||...||.|.:..||.::||.::..::::.:| .:
  Rat   287 DREELKPIRLLGSTIPLCSAQWERLFNTSRIPGEETDTIQHIKDSRHIVVYHRGRYFKVWLY-HD 350

  Fly   254 GKLIAAPCLAAQLENIV--LKETQVG-VPYGILTTDSRDNWAEAYEYLVETPGNRDALKTIQGAL 315
            |:|:....|..|::.|:  ..|.|.| .....||...|..||:..:.......|:.:|..::.|.
  Rat   351 GRLLRPRELEQQMQQILDDPSEPQPGEAKLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAA 415

  Fly   316 FTVSLDEGTILKEG--EETDELIL-----SLIHGSGSKINSGNRWMDKTIQLVVNPNGNVGFTYE 373
            |.|:|||.   ::|  ||..|..:     ||:||     ...:||.||:|..||..|..:|...|
  Rat   416 FFVTLDES---EQGYREEDPEASIDSYAKSLLHG-----RCFDRWFDKSITFVVFKNSKIGINAE 472

  Fly   374 HSPAEGQPIAMMMDYVVQKMKEDPSFGQSG------SQDFAPAQKIQFSSSNKSLEKSLNVAQEN 432
            ||.|:...:..:.:||:........:.:.|      :.:.....::|:....: .::.::.:..:
  Rat   473 HSWADAPVVGHLWEYVMATDVFQLGYSEDGHCKGDTNPNIPKPTRLQWDIPGE-CQEVIDASLSS 536

  Fly   433 VDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGR 497
            ...||:.:.:....|:.|||..|||.|..||:|:|:|||||.||...:....||::..|:|..||
  Rat   537 ASLLANDVDLHSFPFDSFGKGLIKKCRTSPDAFIQLALQLAHYKDMGKFCLTYEASMTRLFREGR 601

  Fly   498 TETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGL----KL 558
            |||:|||:.||..|.:||.||..|.::|....:.|...||...:||:.|.|:||||..|    |.
  Rat   602 TETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIACEKHQHLYRLAMTGAGIDRHLFCLYVVSKY 666

  Fly   559 MALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFM-------------GYGPATDDGYACC 610
            :|::     ..|.|.   |.|..:|:||||...:.....             |:||..||||...
  Rat   667 LAVD-----SPFLKE---VLSEPWRLSTSQTPQQQVELFDFEKNPDYVSCGGGFGPVADDGYGVS 723

  Fly   611 Y-NPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEM 647
            | ...:|.|...||:....|.||..:|.|.|.|:..::
  Rat   724 YIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDI 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	175/620 (28%)
Cpt1a	NP_113747.2	CPT_N	1..47	CDD:406797
		Carn_acyltransf	171..761	CDD:395612	175/618 (28%)
		Coenzyme A binding. /evidence=ECO:0000250	555..567		6/11 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920