Protein Alignment CRAT and CPT2

DIOPT Version :9

• Sequence 1: NP_001287195.1
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_000089.1
• Gene: CPT2 / 1376
• HGNCID: 2330
• Length: 658
• Species: Homo sapiens
• Alignment Length: 653
• Identity: 168/653 - (25%)
• Similarity: 313/653 - (47%)
• Gaps: 85/653 - (13%)

  Fly    50 IAKKVLPASSYSTVQKTIPLEQPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLK 114
            :.:.::|...|          |.:|.:..:..||:|:.|:::..:|||...:|::.:.....|..
Human    35 LQRSIVPTMHY----------QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFEN 89

  Fly   115 KQGREL--QLLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTF---PKQNFRD--SRAF 172
            ..|:||  ||:..:..:|..::::..|.. .||:.||.|.:..:|.|.|   ||..:.|  :||
Human    90 GIGKELHEQLVALDKQNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRA- 152

  Fly   173 VDYTARVI-------YGLGEFNDMVHANK--------------IP-------IVKMGKNELDNSQ 209
            .:.|...|       .||.| .::.|.|.              :|       ...:....||.||
Human   153 TNMTVSAIRFLKTLRAGLLE-PEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQ 216

  Fly   210 FGKVFGTCRIPRRGTDEIVYNPDSDYVVVIYKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKET 274
            :.::|.:.|:|:...||:..:..:.:::|:.|.:||...:..::|.:::...:.|.|:.|:...:
Human   217 YFRLFNSTRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSS 281

  Fly   275 QV-GVPYGILTTDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEGTILKEGEETDELILS 338
            .. ..|...||:::||.|||..:.|:.: ||.::|:.:..|:|.:.||:..|    ::...|..:
Human   282 PAPEFPLAYLTSENRDIWAELRQKLMSS-GNEESLRKVDSAVFCLCLDDFPI----KDLVHLSHN 341

  Fly   339 LIHGSGSKINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSF---G 400
            ::||.|:     |||.||:..|::..:|:....:|||..:|..:....:.|.:...:.|:.   .
Human   342 MLHGDGT-----NRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQS 401

  Fly   401 QSGSQD-FAPAQKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDS 464
            |..:.| ....||:.|..:: :|:..:..|:|..|.....|.:..::|...||:|:|||:|.||:
Human   402 QPATTDSTVTVQKLNFELTD-ALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDA 465

  Fly   465 FVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFSRA-MQDPNVTDQERAAK 528
            ..|:|.|:||.:.:.:..|.|||.....|..|||||||..|..:...|.| :::|:   :..|.:
Human   466 VAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPS---RHSAGE 527

  Fly   529 LREAVVS----HQTYAKLALQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQV 589
            |::.:|.    |....|.|..|:|.||||..|:.:|......:||.:..|.:.:.:|..:|||.:
Human   528 LQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTSTL 592

  Fly   590 ATKYDAFMGYGPATDDGYACCYNPRDNDIILAISAWRHCPITDH-----LKFVKTLEQSFFEMKN 649
            ::......|:.|...||:...|...||        |..|.::.:     .:|::.:|::..:|.:
Human   593 SSPAVNLGGFAPVVSDGFGVGYAVHDN--------WIGCNVSSYPGRNAREFLQCVEKALEDMFD 649

  Fly   650 VLE 652
            .||
Human   650 ALE 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	162/623 (26%)
CPT2	NP_000089.1	Carn_acyltransf	49..648	CDD:279140	162/623 (26%)
		Coenzyme A binding. /evidence=ECO:0000250	452..464		7/11 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920