Protein Alignment CRAT and CPT1A

DIOPT Version :9

• Sequence 1: NP_001287195.1
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_005273819.1
• Gene: CPT1A / 1374
• HGNCID: 2328
• Length: 805
• Species: Homo sapiens
• Alignment Length: 632
• Identity: 187/632 - (29%)
• Similarity: 292/632 - (46%)
• Gaps: 93/632 - (14%)

  Fly    71 QPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETGSKEKNWL 135
            |.:|.:..|..:::|:||::.:|.||:..|:|:|...:..:|....|..||..|:.......|::
Human   200 QTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYV 264

  Fly   136 AHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTARVIYGL------GEFNDMVHA-- 192
            :..|.:..||..|.|:.|         ..|:        |...::|.|      ....:.:||
Human   265 SDWWEEYIYLRGRGPLMV---------NSNY--------YAMDLLYILPTHIQAARAGNAIHAIL 312

  Fly   193 ---NKI------PIVKMGKN-ELDNSQFGKVFGTCRIPRRGTDEIVYNPDSDYVVVIYKNHFYQL 247
               .|:      ||..:|.. .|.::|:.::|.|.|||...||.|.:..||.::||.::..::::
Human   313 LYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKV 377

  Fly   248 KIYSKEGKLIAAPCLAAQLENIV--LKETQVG-VPYGILTTDSRDNWAEAYEYLVETPGNRDALK 309
            .:| .:|:|:....:..|::.|:  ..|.|.| .....||...|..||...:.......|:.:|.
Human   378 WLY-HDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLD 441

  Fly   310 TIQGALFTVSLDEGTILKEGEET-------DELILSLIHGSGSKINSGNRWMDKTIQLVVNPNGN 367
            .::.|.|.|:|||   .:||..:       |....||:||     ...:||.||:...||..||.
Human   442 AVEKAAFFVTLDE---TEEGYRSEDPDTSMDSYAKSLLHG-----RCYDRWFDKSFTFVVFKNGK 498

  Fly   368 VGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSFGQSG--SQDFAP----AQKIQF---SSSNKSLE 423
            :|...|||.|:...:|.:.:||:........:.:.|  ..|..|    ..::|:   ....:.:|
Human   499 MGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIE 563

  Fly   424 KSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESA 488
            .|||.|    :.||:.:......|..|||..|||.|..||:|||:|||||.||...:....||::
Human   564 TSLNTA----NLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEAS 624

  Fly   489 HLRIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHL 553
            ..|:|..|||||:|||:.||..|.|||.||..|.::|....:.|...||...:||:.|.|:||||
Human   625 MTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHL 689

  Fly   554 LGL----KLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFM-------------GYGP 601
            ..|    |.:|:|     ..|.|.   |.|..:|:||||...:.....             |:||
Human   690 FCLYVVSKYLAVE-----SPFLKE---VLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGP 746

  Fly   602 ATDDGYACCY-NPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEM 647
            ..||||...| ...:|.|...||:...||.||..:|.:.|:::..::
Human   747 VADDGYGVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDI 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	186/629 (30%)
CPT1A	XP_005273819.1	CPT_N	33..78	CDD:293093
		Carn_acyltransf	203..793	CDD:279140	186/627 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920