Protein Alignment CRAT and Chat

DIOPT Version :9

• Sequence 1: NP_001287195.1
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_034021.1
• Gene: Chat / 12647
• MGIID: 88392
• Length: 645
• Species: Mus musculus
• Alignment Length: 644
• Identity: 202/644 - (31%)
• Similarity: 325/644 - (50%)
• Gaps: 47/644 - (7%)

  Fly    50 IAKKVLPASSYSTVQKTIPLEQPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLK 114
            |.:||.|.   ..||.:...|..:|.|..|.||::||..::..::.|:..|:|::.:.|...|..
Mouse     3 ILEKVPPK---MPVQASSCEEVLDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGA 64

  Fly   115 K--QGRELQLLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTA 177
            .  .|..||..|.|...|..||::..||...||..|..:.|..||.:.|.:|:|:|:...:.:.|
Mouse    65 PGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAA 129

  Fly   178 RVIYGLGEFNDMVHANKIPIVKMGKNELDN-----SQFGKVFGTCRIPRRGTDEIVYN-----PD 232
            .:|.|:..:..::.:..|| ....|.:|..     .|:.::|.:.|:|....|.:|..     |:
Mouse   130 SLISGVLSYKALLDSQSIP-TDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPE 193

  Fly   233 SDYVVVIYKNHFYQLKIY-----SKEGKLIAAPCLAAQLENIV---LKETQVGVPYGILTTDSRD 289
            .::|:|...|.|:.|.:.     ..||.|.      .||..||   ..|.:...|.|:||:|.|.
Mouse   194 PEHVIVACCNQFFVLDVVINFRRLSEGDLF------TQLRKIVKMASNEDERLPPIGLLTSDGRS 252

  Fly   290 NWAEAYEYLVETPGNRDALKTIQGALFTVSLD-EGTILKEGEETD-ELILSLIHGSGSKINSGNR 352
            .||:|...|::...|||:|..|:..:..|.|| .||    |:.:| ...|.|:||.|..:|..||
Mouse   253 EWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGT----GDLSDTHRALQLLHGGGCSLNGANR 313

  Fly   353 WMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQKMKE-DPSFGQSGSQDFAPA-QKIQF 415
            |.||::|.||..:|..|...||||.:|..:....:::::.|.. :....::.|....|| :::::
Mouse   314 WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTGNKKLVRADSVSELPAPRRLRW 378

  Fly   416 SSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSE 480
            ..|.:: :..|..:.|.:.::...|...|.||:.:||.|||||:..||.|:|:|||||:|:::..
Mouse   379 KCSPET-QGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDGFIQVALQLAYYRLYQR 442

  Fly   481 PPAQYESAHLRIFDGGRTETIRSCSNESLAFSRAMQDPN--VTDQERAAKLREAVVSHQTYAKLA 543
            ....||||.:|.|..||.:.|||.:.|:|||.:||.|..  |...|:...|:.|:.:...|..:|
Mouse   443 LVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAVLASEKLQLLQRAIQAQTEYTVMA 507

  Fly   544 LQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFMGYGPATDDGYA 608
            :.|..:|.|||.|:.:|.:..|..||.|....::.|:.|.:|||||.|..:.|..|||...:||.
Mouse   508 ITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFILSTSQVPTTMEMFCCYGPVVPNGYG 572

  Fly   609 CCYNPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEMKNV------LEKNPPETKSK 661
            .||||:...|...||::..|..|..::|.:.:..|..:|:::      .|..||..|.:
Mouse   573 ACYNPQPEAITFCISSFHGCKETSSVEFAEAVGASLVDMRDLCSSRQPAEGKPPTAKER 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	190/599 (32%)
Chat	NP_034021.1	Carn_acyltransf	24..612	CDD:279140	190/599 (32%)
		Coenzyme A binding. /evidence=ECO:0000250	413..425		7/11 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3717
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm43021
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2058
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850