Protein Alignment CG10286 and heatr3

DIOPT Version :10

• Sequence 1: NP_649649.1
• Gene: CG10286 / 40786
• FlyBaseID: FBgn0037439
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001011439.1
• Gene: heatr3 / 496925
• XenbaseID: XB-GENE-5805167
• Length: 677
• Species: Xenopus tropicalis
• Alignment Length: 696
• Identity: 189/696 - (27%)
• Similarity: 309/696 - (44%)
• Gaps: 93/696 - (13%)

  Fly     1 MGKVRKVKTRTPSGVDTSAEIDVESAGEAEGCGPIEA--ICVHLQQANVEEKLNGLHSFAVLALR 63
            |||.|..:.:......|.........||.|.|..::|  :...||..:.|.:.....|.:.|...
 Frog     1 MGKSRARRFKPGLFAPTLPVRQSNGHGEQENCETLQAEELLQKLQSPSPEVREFACASISRLVQL 65

  Fly    64 KEKVPEIRDSELVRIAAPLLCDKESAIRNAAAGAFRNLSVF-GTEVCDFLVENDILTALLTLVR- 126
            |:.:|.....:.||...|||.|...::|..||||.||||.. |.:|||.:|..||:|.|:.|:|
 Frog    66 KKVIPSFLQKDAVRCLGPLLLDTCLSVRETAAGALRNLSTCGGFDVCDDMVTRDIMTPLVVLLRE 130

  Fly   127 --------------SYDLTKGGFENELHADTFQQAIHLLRNLCESSPTATEALNQANFLSSLLLG 177
                          |.|:||...:     |...||:::|.|:||||..|....|:...:..:|..
 Frog   131 CATSLDVNIESTIKSNDITKNYVQ-----DIANQALNVLWNVCESSSKALCIFNKERCVDIVLQC 190

  Fly   178 FDYRKFGLEVAISVAQLVLVVSENNSSSWNVLASSTI--LPELLVAPTESHAQLYLNALAAGILC 240
            ....:...|:|||.|..:..|:|:|....|.:.:|::  |..:::|...:.....|..||||.:.
 Frog   191 LSKFQTNTEMAISAAYCLQTVTEDNQDLLNSVDTSSLQMLESVMLASANNMDIRLLQTLAAGSIW 255

  Fly   241 N----VPACAAAHT-REILNSLDKLLSIDPQ---AQLQSCKSEILNA-----KSKNEAPVLEISM 292
            |    :|:...|.: ..||....::|::|..   .|::..:|:.|:|     :::....:|:.|:
 Frog   256 NLRERIPSSMQADSITAILRIFAEVLTVDAGQYIVQMKEAESKRLSAATVEHETEETTAILDTSL 320

  Fly   293 ETEDMTETQSANQSKPNQCD-----AEVALKNLEHLLDAQRLVAEIITNLGSSDEQSN--WDTDS 350
            ..||......:||.:.....     |...::....||.||:...|||.|:..||:.|:  |:..|
 Frog   321 NEEDEKIDGFSNQKRLTDISDLIPAANDEIRQATALLVAQKTALEIIVNMCCSDDPSDDEWEMLS 385

  Fly   351 EHSESESVADYDMEDETADSG---------SGGLPANFLETIKQNKVIEK----------LWQKA 396
            ...||    |..:|....|||         |..:.:..|..:...||.||          :.|:|
 Frog   386 SSDES----DLGLEKSLNDSGGQLLSPLCLSDEVHSALLNHLIPKKVFEKTRFPNSSALNICQEA 446

  Fly   397 QPLQPAVENLVSQQENIKEKVEKLRVSYLICLQNLCNVLPPEDLGGCSNLYNMWMILGQQAFRGS 461
            .|.:|.:..|.:           ::...|.||.|:.:|...|:|||.|.|..:...|.:..|..|
 Frog   447 SPWKPMIPRLYT-----------IQYRALTCLNNILSVFDVENLGGASALQELAQHLLEIVFTQS 500

  Fly   462 EDV----SVMEAITSLMRSSLSLLKSRKDLFGQMTENDLNMIIEGASKCTDINIRVNWNRMLGTL 522
             ||    ..:||.:|.:|:.|.::.| |.:...|....:..:.|...:..:.:.|||...:||..
 Frog   501 -DVQNQDEFLEAASSAVRALLQIMAS-KGIPQCMMPEQIMSLCEVCVQSKNTSARVNAVSILGIT 563

  Fly   523 GSLLSE-----PLVKAIVLFLLTYCAQEDDLWALSEGLDALMDIFAVDDWPQIIA-ELEMCDRVQ 581
            ||:|::     ..:|||...||...|.:..|......||||:|:||..:..:..| |:.:...:.
 Frog   564 GSVLAKTENTSDTLKAIGSLLLGIAANDSSLVVSGGALDALIDVFADGEESEKAALEISLLQELG 628

  Fly   582 ALEELFKSKLRQQRREL--KERRATVQTVKTNFSRFVFYLNKNCKK 625
            .::.:||:|:|:..||.  .::...:..|:||..||:.||....||
 Frog   629 KIQPVFKTKIRKDGREKYNMDQLCVLDNVRTNLRRFISYLESVEKK 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10286	NP_649649.1	Syo1_like	41..621	CDD:474028	177/648 (27%)
heatr3	NP_001011439.1	Syo1_like	2..670	CDD:240521	186/689 (27%)
		HEAT repeat	39..67	CDD:293787	5/27 (19%)
		HEAT repeat	76..102	CDD:293787	11/25 (44%)