Protein Alignment CG10286 and heatr3

DIOPT Version :10

• Sequence 1: NP_649649.1
• Gene: CG10286 / 40786
• FlyBaseID: FBgn0037439
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_957183.1
• Gene: heatr3 / 393863
• ZFINID: ZDB-GENE-040426-1876
• Length: 682
• Species: Danio rerio
• Alignment Length: 689
• Identity: 194/689 - (28%)
• Similarity: 317/689 - (46%)
• Gaps: 71/689 - (10%)

  Fly     1 MGKVRKVKTR----TPSGVDTSAEIDVESAGEAEGCGPIEAICVHLQQANVEEKLNGLHSFAVLA 61
            |||.:..|.:    :|.|:..:|..:.....|.|...|...:...||..:.:.:.....|.:.:.
Zfish     1 MGKTKNPKFKRSQFSPDGLAATAVKNTVEEAEDEEDSPAAELLEKLQSPSADVREYACASISRIV 65

  Fly    62 LRKEKVPEIRDSELVRIAAPLLCDKESAIRNAAAGAFRNLSVF-GTEVCDFLVENDILTALLTLV 125
            ...:.:|.....:.||...|||.|....:|..|.||.||||.. |.|||:.:|..|:||.|..|:
Zfish    66 QENQTLPGFLQRDAVRKIGPLLLDHSLTVRETATGALRNLSASGGPEVCEDMVRQDVLTPLSALL 130

  Fly   126 RS-------YDLTKGGFENELHADTFQQAIHLLRNLCESSPTATEALNQANFLSSLLLGFDYRKF 183
            |.       ...:|.|.:..:. |...:|::||.||||||.||....|:|..:..||........
Zfish   131 RECCAGFGVNSPSKKGQKTSVE-DVANEAVNLLWNLCESSSTAVSVFNKAGLVDVLLQCLQKHPQ 194

  Fly   184 GLEVAISVAQLVLVVSENNSS---SWNVLASSTILPELLVAPTESHAQLYLNALAAGILCN---- 241
            .:|:|||.|..:..|:|.||.   |.|. |...:|..:|.:...|...:.|..||||.|.|
Zfish   195 NMELAISAAHCLHTVTEENSELIRSGNA-AVFGVLDNILSSTHTSMENILLRTLAAGSLWNLKNG 258

  Fly   242 VPACAAAHTREIL-NSLDKLLSID-----PQ------AQLQSCKSEILNAKSKNEAPVLEISMET 294
            :.:...:||...| ::|...||:|     ||      |:|....:.:......::.|.   .::.
Zfish   259 LSSAQQSHTLTALASTLSHSLSLDAGELIPQLWRAESARLSKDTTSVTETHHTDQRPA---GLQV 320

  Fly   295 EDMTE---TQSANQSKPN------QCDA-------EVALKNLEHLLDAQRLVAEIITNLGSSDEQ 343
            |:|.|   .|..|..|||      :.|.       .:.|:..:.||.||:...|||.|:..|||.
Zfish   321 EEMEEELNDQKRNGGKPNVQMSRTKNDISDLLPRDRLELREAKALLSAQQTSLEIIVNMCCSDEP 385

  Fly   344 SN--WDTDSEHSESESVADYDMEDETADSGSGGLPANFLETIKQN-KVIEKLWQKAQPLQPAVEN 405
            |:  |:..|...|||..|| .|.|..:...|....:..|.|:..| .:.:::.:||:....|...
Zfish   386 SDDEWEEMSSSDESEMCAD-GMSDTNSSLFSPLCLSAELHTVLLNHSMPQQVLKKAEFPSAAALE 449

  Fly   406 LVSQQENIK---EKVEKLRVSYLICLQNLCNVLPPEDLGGCSNLYNMWMILGQQAFRGSE---DV 464
            |.|:..:.|   :|:::::...|.||.|:.:.:..:.|||.|:|..:...|....|..:|   |.
Zfish   450 LCSKDSSWKCLLKKMQRVQCRALTCLHNILSSMDTDSLGGASSLQAVAQHLSSLVFSSAEVLKDE 514

  Fly   465 SVMEAITSLMRSSLSLLKSRKDLFGQMTENDLNMIIEGASKCTDINIRVNWNRMLGTLGSLLSEP 529
            ..:||:||.:||.|.:: :.|::...||.:.|....|.|:.|..::::||...:||..||.|::.
Zfish   515 EFLEAVTSALRSLLQIM-ATKNISQCMTPHQLMGFCEAATSCDLVSVKVNALAILGITGSSLAKD 578

  Fly   530 LVKAIVL-----FLLTYCAQEDDLWALSEGLDALMDIFAVDDWPQIIAE-LEMCDRVQALEELFK 588
            ...|..|     .||....::.:|....|.||||.|:||..|..:..|: :::...::||:..|:
Zfish   579 KNTADTLQLIGNALLNVATKDANLVVCGEALDALFDVFADGDEAEKAAKNIDLLSSLKALQPGFR 643

  Fly   589 SKLRQQ--RRELKERRATVQTVKTNFSRFVFYLNKNCKK 625
            :|||::  .:...::...:..::.|..||:.||....:|
Zfish   644 AKLRKEGKGKYSPDQLCVLDNIRINLKRFIGYLENLQRK 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10286	NP_649649.1	Syo1_like	41..621	CDD:474028	183/639 (29%)
heatr3	NP_957183.1	Syo1_like	2..679	CDD:240521	192/683 (28%)
		armadillo repeat	71..108	CDD:293788	15/36 (42%)
		armadillo repeat	114..165	CDD:293788	14/51 (27%)