Protein Alignment CG42724 and tcerg1b

DIOPT Version :10

• Sequence 1: NP_001189184.1
• Gene: CG42724 / 40785
• FlyBaseID: FBgn0261641
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_009293957.1
• Gene: tcerg1b / 797473
• ZFINID: ZDB-GENE-101026-4
• Length: 990
• Species: Danio rerio
• Alignment Length: 1116
• Identity: 401/1116 - (35%)
• Similarity: 571/1116 - (51%)
• Gaps: 279/1116 - (25%)

  Fly    74 PIGEHTAQQQALQQQQLQQQQQPQQ---PQQQAPSGANGVTGPPEIWVETKAEDGRSYYYHAVTR 135
            |||....|:.......:.....|..   |....||.........|||||....:|:.|||:|.||
Zfish    85 PIGPPHLQRPPFMPPPMGNMPPPPGMIFPPGMPPSPGAASLPSEEIWVENNTPEGKVYYYNARTR 149

  Fly   136 ETTWSRPDGPAVKIMTQAEVEEM--------AKRPAQAAKTEAKAGETSVEIPPVSSHLTSQPPP 192
            |:.|::|:|  |||:.|:|:..:        |..|..||.....:...:|....||:.  |..|.
Zfish   150 ESAWTKPEG--VKIIQQSELNPLMAAQSGGAAAAPNSAASANVASTTATVVTDTVSTQ--SMSPS 210

  Fly   193 HLMS-QPPPNAA-APLLSQP---------PPNVRQQP--------------------------PP 220
            |.:| .|.|:.: ||..|||         ||.|...|                          |.
Zfish   211 HTLSTSPDPSTSPAPTASQPSITSVVSEMPPVVSTPPVSVSVTPVAVVSVPTVTATVTAVQTMPL 275

  Fly   221 MFQ--PPGMQAPPGFGQ---PPFCMPPPTYGFPGG--PAPAGAPWGVGIPPWQQQQHMQDKPAKS 278
            :.|  |||:...|..|.   ||..:||.....||.  |.|     |:| ||.....|.|...|.|
Zfish   276 LHQSLPPGLPVAPPAGAIPFPPVMVPPFRVPLPGMHIPLP-----GMG-PPLVPMMHPQLTIAAS 334

  Fly   279 LIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAGRGESVWEKPQAL----RDMEAARMAAHSGV 339
            .:...|.|.      ..||||.:..|||.||::....||.||||..|    :|.:.|| ..|:.:
Zfish   335 PMSLAGAIP------LPEWSEFKTADGRIYYYNNRTLESTWEKPFELKERDKDSDKAR-DIHNNI 392

  Fly   340 APAVATAPSGLPPHLLPNPMMHMPPGSGPPGFDPHAAFAAAAAAMKANSENTKAAQAAALEKEAK 404
                     .|...|:.                           |:|.::..|          :|
Zfish   393 ---------NLDLKLID---------------------------MEAKADFGK----------SK 411

  Fly   405 KAAEEKRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPE 469
            :...|:...|||        |.|.|.:||.:.||.|||||||||||.|||:|||:||.|:|||||
Zfish   412 ELPREEDMTEEE--------KATQKGKPVATNPIPGTPWCVVWTGDERVFYYNPTTRLSMWDRPE 468

  Fly   470 DLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDD 534
            :|:.|.|||:.:.|.|              .|.|                ||.::::..:.::.|
Zfish   469 ELVGRADVDRYIQEPP--------------HKRG----------------LDDIKKIGFNKEEID 503

  Fly   535 EVIKIRTESESSVEEVPTKRVRM----ISKSKRAEDAALEAEQRAAKERALVPLEMRVTQFKEML 595
                  |..|..:::.|:|..:.    :.:.:.|:|.|:|||.:||::|||||||.|:.||::||
Zfish   504 ------TAMEDMLDDEPSKAKKRKKDDVKEPEAAKDVAVEAELKAARDRALVPLEARMNQFRDML 562

  Fly   596 REKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDFRSL 660
            .|:.|||||||:|||||||||||||||..|||||||::|||.|||||||||:||:.|.::|||.:
Zfish   563 LERGVSAFSTWDKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERKEKKNKLMQSKDDFRRM 627

  Fly   661 MEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKEDKLLKKEQIRKDFL 725
            ||:|:||.:::||||:.:::||.|::||||:::||.:|.|::...|:::|||...|.:::::||.
Zfish   628 MEDAKLHTRTTFSEFAAKHSKDPRFKAIEKMKDREVMFTEFMTAFRKKDKEDSKNKVDKVKQDFF 692

  Fly   726 DMLRERH-DIERHTRWYDIKKKFESDPRYRMVD-SMYREEYFEDYLHIMKEEKRKEREMREQRER 788
            |:|.:.| ||.:  ||..:|.|.|:|.||:.|: |..|||:::.|:
Zfish   693 DLLSDHHVDITQ--RWSKVKDKLETDQRYKAVESSAAREEFYKQYV------------------- 736

  Fly   789 ERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSEKSKKRDTTPEEG 853
                                               .|.:|..|.|||
Zfish   737 -----------------------------------EKQAKNVDADKE------------------ 748

  Fly   854 EHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQRTLAGHLRDRDKE 918
                                           ||.|::.|:|.|:||||:||||..:...::.|:|
Zfish   749 -------------------------------KELERQARIEASLREREREVQRARSEQTKEIDRE 782

  Fly   919 REHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRERKFNEHIDNLMK 983
            ||.|.|||.|.||.||::|:||:.|.:|.|.:|.||||||||....|:|.::|:.|.:|::.|.|
Zfish   783 REQHKREEAIQHFRALMSDMVRSTDTSWSETRRNLRKDHRWETSSLLERHEKEKLFEDHVEALTK 847

  Fly   984 KKRERFREMLDEISTLQLTSTWKEIKKLIKEDPRYLKYNSD--KGEREFRDYIKDKTMTAKTSLR 1046
            :|:|.||::|||...:.||:.|||:||:||||||.:|::|.  |.:|||.||||||.:.||...|
Zfish   848 RKKEHFRQLLDETPMITLTTAWKEVKKIIKEDPRCMKFSSSDRKKQREFEDYIKDKYIIAKADFR 912

  Fly  1047 ELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVLGFLEELNKRGPPP 1111
            .||:|.||||::|..||:|:..|||:|:.:|:|||||||||.:.|||..:::.::|:|::|||||
Zfish   913 TLLKETKFITYRSRKLIQESDQHLKDIEKVLQNDKRYLVLDCVPEERRKLIMFYIEDLDRRGPPP 977

  Fly  1112 PPTASESTRRN 1122
            ||||||..||:
Zfish   978 PPTASEPCRRS 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42724	NP_001189184.1	WW	112..144	CDD:197736	15/31 (48%)
		PHA03247	<159..369	CDD:223021	69/257 (27%)
		Extensin_2	180..243	CDD:252669	27/104 (26%)
		WW	295..322	CDD:459800	13/26 (50%)
		PRP40	443..>753	CDD:227435	144/314 (46%)
		COG4913	<865..1105	CDD:443941	113/241 (47%)
		FF	930..977	CDD:426471	23/46 (50%)
		FF	983..1036	CDD:128718	30/54 (56%)
tcerg1b	XP_009293957.1	WW	125..156	CDD:459800	14/30 (47%)
		DUF5585	<208..348	CDD:465521	40/151 (26%)
		PRP40	333..950	CDD:227435	305/818 (37%)