Protein Alignment CG42724 and Prp40

DIOPT Version :10

• Sequence 1: NP_001189184.1
• Gene: CG42724 / 40785
• FlyBaseID: FBgn0261641
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: NP_608738.1
• Gene: Prp40 / 33513
• FlyBaseID: FBgn0031492
• Length: 806
• Species: Drosophila melanogaster
• Alignment Length: 1026
• Identity: 225/1026 - (21%)
• Similarity: 356/1026 - (34%)
• Gaps: 343/1026 - (33%)

  Fly   195 MSQPPP--NAAAPLLSQPPPNVRQQPP----PMFQPPGMQAPPGFGQPPFCMPPPTYGFPGGPAP 253
            |:.||.  |..||    |...:...||    |.|.|||..|||                   |..
  Fly     1 MNVPPSVGNGGAP----PGRGIGYTPPGAIVPQFPPPGFGAPP-------------------PPE 42

  Fly   254 AGAPWGVGIPPWQQQQHMQDKPAKSLIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAGRGESV 318
            ..|.:|                              |:|.:.||:||:||||||||::....:|.
  Fly    43 LAAAFG------------------------------VMATSTEWTEHKAPDGRPYYYNQNTKQSS 77

  Fly   319 WEKPQALRDMEAARMAAHSGVAPAVATAPSGLPPHLLPN--PMMHMPPGSGPPGFDPHAAFAAAA 381
            ||||:||.                       .|..||.|  |.......:|...:  |..
  Fly    78 WEKPEALM-----------------------TPAELLHNQCPWKEYRSDTGKVYY--HNV----- 112

  Fly   382 AAMKANSENTKAAQAAALEKEAKKAAEEKRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVV 446
                |..|.........::.:||..|||          |||:||..   ..:||:.:||
  Fly   113 ----ATKETCWEPPPEYVDMKAKAKAEE----------AAAAAKAV---AAMTSSSLAG------ 154

  Fly   447 WTGDSRVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQA 511
                    ...|:...|:            :..|:...| :|.|| |..:.....|.|  |...|
  Fly   155 --------MVPPAALASI------------LPAALPVAP-RLPTP-EIHSPLTPSSNE--NSSSA 195

  Fly   512 KSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAA 576
            ..|..|..|..:                         |||.:..:   |..::|.|.:..::|.|
  Fly   196 MDQAMAATLAAI-------------------------EVPQQNAK---KDDKSESAVVFKDKREA 232

  Fly   577 KERALVPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYLLLTS-KERKQVFEKYVKDRAE 640
                       :..|||:||:::|.:.:.|::.:..|..||||....: .||||.|..|...:.:
  Fly   233 -----------IESFKELLRDRNVPSNANWDQCVKIISKDPRYAAFKNLNERKQTFNAYKTQKIK 286

  Fly   641 EERKEKRNKMRQKREDFRS-LMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVE 704
            :||:|.|.|.::.:||... ||...:::.:..:....:..|....:.|:.: .:|..::.:.|..
  Fly   287 DEREESRLKAKKAKEDLEQFLMSSDKMNSQMKYFRCEEVFAGTRTWTAVPE-PDRRDIYEDCIFN 350

  Fly   705 VRRREKEDKLLKKEQIRKDFLDMLRERHDIERHTRWYDIK------KKFESDPRYRMVDSMYREE 763
            :.:||||:..|.|::..|...::|.....|...|.|.:.:      ..|::|.....:|.
  Fly   351 LAKREKEEARLLKKRNMKVLGELLESMTSINHATTWSEAQVMLLDNVAFKNDVTLLGMDK----- 410

  Fly   764 YFEDYLHIMKEEKRK-EREMREQRERERHRELKSDRKEK-------DKEKDKGRKDR-------- 812
              ||.|.:.:|..|. |:|..|:||||:.|..:..||.:       |...::|:...
  Fly   411 --EDALIVFEEHIRTLEKEEDEEREREKKRMKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVELY 473

  Fly   813 -------------GRSRSKDKDR-----EHKSSKEKDKDK------EEKSKSEKSK--------- 844
                         |:|.|...|.     |:..::..|:.|      :||:...::|
  Fly   474 PIISADLRFSAMLGQSGSTPLDLFKFYVENLKARFHDEKKIIREILKEKAFVVQAKTSFEDFATV 538

  Fly   845 ----KRDTTPEEG----------EHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQ 895
                ||..:.:.|          |..|..|:|..    ..||.|.|:.|.|.|.:..|..:.|.:
  Fly   539 VCEDKRSASLDAGNVKLTYNSLLEKAEAIEKERM----KEEVRRLRKLENEIKNEWLEANVSVAE 599

  Fly   896 SIREREKEVQRTLAGHLRDRD-----------KERE-----HHMREECIGHFTALLTDLVRTPDF 944
            .....:|.|:...|..|.:::           ||.|     ||.|..
  Fly   600 PYESAKKLVEHLEAFALYEKEIGVEKIWEDFVKESEDACSHHHSRSR------------------ 646

  Fly   945 TWKEVKRQLRKDHRWELIESLDREDRERKFNEHIDNLMKKKRERFREMLDEISTLQLTSTWKEIK 1009
                 |.:..|.|: :.:.|:.|.|.|   ||||: :.|.||.|.:.....::::....:.|.:|
  Fly   647 -----KSKKNKKHK-KRVRSVSRSDIE---NEHIE-VEKSKRRRSKTRSHSLTSIGSIESEKLLK 701

  Fly  1010 KLIKEDPRYLKYNSDKGEREFRDYIKDKTMTAKTSLRELLQECKFITHKSSDLIKENPNHLKEIQ 1074
            |..|   |..|......|       .|.........:.|||         :|....:|...|:.:
  Fly   702 KKKK---RKNKLRGSSCE-------SDVPGIQSPGTQALLQ---------NDSNSHSPAKKKKKE 747

  Fly  1075 DILKNDKRYLVLDHMEEERNTIVLGFLEELNKRGPP--PPPTASESTRRNK 1123
            ...|.|||:                  ...|:.|.|  |..:...|..||:
  Fly   748 KRAKKDKRH------------------NRHNRSGTPLSPAQSVESSGSRNE 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42724	NP_001189184.1	WW	112..144	CDD:197736
		PHA03247	<159..369	CDD:223021	47/181 (26%)
		Extensin_2	180..243	CDD:252669	17/53 (32%)
		WW	295..322	CDD:459800	15/26 (58%)
		PRP40	443..>753	CDD:227435	67/317 (21%)
		COG4913	<865..1105	CDD:443941	52/255 (20%)
		FF	930..977	CDD:426471	8/46 (17%)
		FF	983..1036	CDD:128718	11/52 (21%)
Prp40	NP_608738.1	PRP40	54..634	CDD:227435	158/707 (22%)