Protein Alignment CG42724 and Tcerg1

DIOPT Version :10

• Sequence 1: NP_001189184.1
• Gene: CG42724 / 40785
• FlyBaseID: FBgn0261641
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_006254735.1
• Gene: Tcerg1 / 307474
• RGDID: 1311748
• Length: 1098
• Species: Rattus norvegicus
• Alignment Length: 1173
• Identity: 426/1173 - (36%)
• Similarity: 593/1173 - (50%)
• Gaps: 339/1173 - (28%)

  Fly    96 PQQPQQQAPSGANGVTGPPEIWVETKAEDGRSYYYHAVTRETTWSRPDGPAVKIMTQAEVEEM-- 158
            |..|...|| ||..:....|||||.|..||:.|||:|.|||:.|::|||  ||::.|:|:..|
  Rat   117 PGMPPGTAP-GAPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLA 178

  Fly   159 --------------------------AKRPAQAAKTEAKA------------------------- 172
                                      |:..||||:.:|:|
  Rat   179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAAQAQAQAQAQAQAQAQAQAQAQVQAQAVGAPT 243

  Fly   173 GETSVEIPPVSSHLTSQPP-------------------PHLMSQPPPNA---------------- 202
            ..||...|.||:...:..|                   |....|.|.:|
  Rat   244 PTTSSPAPAVSTSAPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPT 308

  Fly   203 AAPLLSQPPPNVRQQPP--PMFQPPGMQAPPGFGQPPFCMPPPTYGFPGGPAP---------AGA 256
            |.|:.:.|.|:.:..||  |...|....|.|.|  ||..:||.....||.|.|         ...
  Rat   309 ATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAF--PPVMVPPFRVPLPGMPIPLPGVAMMQIVSC 371

  Fly   257 PW---------GV--GI-PPWQQQQHMQDKPAKSLIIKPGVIDPAVIARA---AEWSEHRAPDGR 306
            |:         ||  |: ||.....|.|...|.|         ||.:|.|   :||:|::..||:
  Rat   372 PYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAAS---------PATLAGATAVSEWTEYKTADGK 427

  Fly   307 PYYFHAGRGESVWEKPQALRDMEAARMAAHSGVAPAVATAPSGLPPHLLPNPMMHMPPGSGPPGF 371
            .||::....||.|||||.|::.|........   |....:...||
  Rat   428 TYYYNNRTLESTWEKPQELKEKEKLDEKIKE---PIKEASEEPLP-------------------- 469

  Fly   372 DPHAAFAAAAAAMKANSENTKAAQAAALEKEAKKAAEEKRKKE-EEQKKAAASAKQTDKSRPVTS 435
                        |:...|:.|       |:..|:..||.:::| .|::|||      .|::||.:
  Rat   470 ------------METEEEDPK-------EEPIKEIKEEPKEEEMTEEEKAA------QKAKPVAT 509

  Fly   436 TPIAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERP-----EQLK-----T 490
            |||.|||||||||||.|||||||:||.|:||||:||:.|.||||.:.|.|     |.:|     .
  Rat   510 TPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGLEDMKKLRHPA 574

  Fly   491 PQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRV 555
            |...|.:..|.|.....:||       :.::::        ::||.||.:            ||.
  Rat   575 PTMLSIQKWQFSMSAIKEEQ-------ELMEEM--------NEDEPIKAK------------KRK 612

  Fly   556 RMISKS----KRA--------------EDAALEAEQRAAKERALVPLEMRVTQFKEMLREKDVSA 602
            ||..|.    .||              ::||:|||.:||:|||:||||.|:.|||:||.|:.|||
  Rat   613 RMSKKPFMWIARASLFRRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSA 677

  Fly   603 FSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDFRSLMEEARLH 667
            ||||||||||||||||||||..|||||||::|||.||||||:||:||:.|.:|||:.:||||:.:
  Rat   678 FSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFN 742

  Fly   668 GKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKEDKLLKKEQIRKDFLDMLRERH 732
            .:::||||:.::|||.|::||||:::||:||||::...|::||||...:.|:|:.||.::| ..|
  Rat   743 PRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELL-SNH 806

  Fly   733 DIERHTRWYDIKKKFESDPRYRMVD-SMYREEYFEDYLHIMKEEKRKEREMREQRERERHRELKS 796
            .::..:||..:|.|.||||||:.|| |..||:.|:.|:
  Rat   807 HLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI--------------------------- 844

  Fly   797 DRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSEKSKKRDTTPEEGEHREESER 861
                                       .|.:|..|.:||
  Rat   845 ---------------------------EKIAKNLDSEKE-------------------------- 856

  Fly   862 EERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQRTLAGHLRDRDKEREHHMREE 926
                                   ||.|::.|:|.|:||||:|||:..:...::.|:|||.|.|||
  Rat   857 -----------------------KELERQARIEASLREREREVQKARSEQTKEIDREREQHKREE 898

  Fly   927 CIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRERKFNEHIDNLMKKKRERFRE 991
            .|.:|.|||:|:||:.|.:|.:.:|.||||||||....|:||::|:.|||||:.|.|||||.||:
  Rat   899 AIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ 963

  Fly   992 MLDEISTLQLTSTWKEIKKLIKEDPRYLKYNSD--KGEREFRDYIKDKTMTAKTSLRELLQECKF 1054
            :|||.|.:.|||||||:||:||||||.:|::|.  |.:|||.:||:||.:|||...|.||:|.||
  Rat   964 LLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKF 1028

  Fly  1055 ITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVLGFLEELNKRGPPPPPTASEST 1119
            ||::|..||:|:..|||:::.||:|||||||||.:.|||..:::.::::|::|||||||||||.|
  Rat  1029 ITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPT 1093

  Fly  1120 RRN 1122
            ||:
  Rat  1094 RRS 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42724	NP_001189184.1	WW	112..144	CDD:197736	17/31 (55%)
		PHA03247	<159..369	CDD:223021	69/295 (23%)
		Extensin_2	180..243	CDD:252669	22/99 (22%)
		WW	295..322	CDD:459800	11/26 (42%)
		PRP40	443..>753	CDD:227435	159/337 (47%)
		COG4913	<865..1105	CDD:443941	118/241 (49%)
		FF	930..977	CDD:426471	24/46 (52%)
		FF	983..1036	CDD:128718	34/54 (63%)
Tcerg1	XP_006254735.1	WW	137..162	CDD:459800	14/24 (58%)
		Herpes_BLLF1	<239..>327	CDD:282904	16/87 (18%)
		PRP40	404..1018	CDD:227435	307/801 (38%)
		FF	1015..1074	CDD:426471	31/58 (53%)