Protein Alignment CG42724 and tcer-1

DIOPT Version :9

• Sequence 1: NP_001189184.1
• Gene: CG42724 / 40785
• FlyBaseID: FBgn0261641
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: NP_001370832.1
• Gene: tcer-1 / 174150
• WormBaseID: WBGene00022855
• Length: 914
• Species: Caenorhabditis elegans
• Alignment Length: 1132
• Identity: 326/1132 - (28%)
• Similarity: 496/1132 - (43%)
• Gaps: 326/1132 - (28%)

  Fly    26 SPPEAGLNGNGSG---SGSTSQETP------------------NYGVAILKEKPSEAHRSKPFNA 69
            :||  |..|.|.|   .|.:|...|                  .||||   ..........|:|
 Worm    75 APP--GFAGRGRGFATPGMSSGFAPRGRGMPPGRGGYMPPYRGGYGVA---PNGGPGAYGGPYN- 133

  Fly    70 FSGRPIGEHTAQQQALQQQQLQQQQQPQQPQQQAPSGANGVTGPPEIWVETKAEDGRSYYYHAVT 134
              |.| |.:.||...         ..||. |:|.....:|.....|:||||:..:|:.|:||.|.
 Worm   134 --GGP-GAYGAQAPG---------PNPQD-QEQRLKRLSGCEEGQELWVETETAEGKKYFYHPVN 185

  Fly   135 RETTWSRPDGPAVKIMTQAEVEEMAKRPAQAAKTEAKAGETSVEIPPVSSHLTSQPPPHLMSQPP 199
            |.|.|.||..  .||:||.|:.::..|..:..|..                  .:..||
 Worm   186 RNTIWERPQN--AKIVTQPELAQLIHRATEEEKNR------------------EERMPH------ 224

  Fly   200 PNAAAPLLSQPPPNVRQQPPPMFQPPGMQAPPGFGQPPFCMPPPTYGFPGGPAPAGAPWGVGIPP 264
                                              ||.|
 Worm   225 ----------------------------------GQIP--------------------------- 228

  Fly   265 WQQQQHMQDKPAKSLIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAGRGESVWEKPQALRDME 329
                |:..|                      .|:|..|||||.|||::...|:.||||:||.|.|
 Worm   229 ----QNPDD----------------------AWNEFNAPDGRKYYFNSITQENTWEKPKALIDQE 267

  Fly   330 AARMAA-----HSGVAPAVATAPSGLPPHLLPNPMMHMPPGSGPPGFDPHAAFAAAAAAMKANSE 389
            ....|:     .:.:|.|.|.|.:.|.. .:.........|.|.|.....|:.||||||:.|.
 Worm   268 NGGGASPEPVQSAAIAEAQAKAQAALAA-FMAQQKTSSNGGGGMPLSKAQASGAAAAAAVNAE-- 329

  Fly   390 NTKAAQAAALEKEAKKAAEEKRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVVWTGDSRVF 454
                                             :||:.|.:||::|||::|||||||||||.:||
 Worm   330 ---------------------------------AAKKKDSTRPISSTPVSGTPWCVVWTGDDKVF 361

  Fly   455 FYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQ 519
            ||||||:.|||:||.|...||||||.|...|         |.:||    ||.||.:.:|:.::
 Worm   362 FYNPSTKCSVWERPPDTYGREDVDKLVQNPP---------SPKAE----EENNQSKKESESES-- 411

  Fly   520 LDQVQRVDADDDDDDEVIKIRTE--SESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERALV 582
                   ::|:|...:..|.|.|  .|:.:.....::.|.....::..|.|:|||.:|||||..|
 Worm   412 -------ESDEDGPPKAKKSRAEKKKEALIAAQKKEKERPRQMLQKPVDPAIEAEMQAAKEREKV 469

  Fly   583 PLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKR 647
            |||.|:.||||||.||:||..||:||||.|||||.|||.|.:.||:..|:.:.:::.|.|:.|:|
 Worm   470 PLEERLKQFKEMLEEKNVSTSSTFEKELSKIVFDKRYLSLGATERRACFDAFCREKIESEKAERR 534

  Fly   648 NKMRQKREDFRSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKED 712
            .::::.:|:|:.|:.|..|:|:||:|.|:.:..||.||:|:|:.|:||..||:::.|:.::||::
 Worm   535 KRVKEAKEEFQKLLAECELNGRSSYSSFTSKFGKDPRYKAVERNRDREDAFNDFVGELHKKEKDE 599

  Fly   713 KLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRYRMVD-SMYREEYFEDYLHIMKEEK 776
            |..|||:::..|:.:|.|:..:.|.::|...||..|.:.||..:| |..||..|.:::..:.:|.
 Worm   600 KRAKKEKLKAAFVKLLEEQTGLTRKSKWSTTKKTLEDEERYIALDSSSTRESLFREFVANLGDET 664

  Fly   777 RKEREMREQRERERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSE 841
            ..:.|
 Worm   665 ASDIE------------------------------------------------------------ 669

  Fly   842 KSKKRDTTPEEGEHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQR 906
                                                     :::||||:|..:.:|..|:|||:.
 Worm   670 -----------------------------------------EEQEREKRLAAQTAIANRQKEVEA 693

  Fly   907 TLAGHLRDRDKEREHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRE 971
            .|...||:|.||.|.....|....:..||.||:::.:.:|.|.:|.||||.|:...:.||:..:|
 Worm   694 ELGNQLRERTKESEKQKMGEHEDTYRNLLIDLIKSTENSWHEARRILRKDERYANCDMLDKTRKE 758

  Fly   972 RKFNEHIDNLMKKKRERFREMLDEISTLQLTSTWKEIKKLIK-EDPRYLKYNSD---KGEREFRD 1032
            ..|::||.:|.:|:||.|.::||....:.....|::.||:|: |:..::|..|:   |.||:|||
 Worm   759 SLFDDHIKSLERKRREAFFQVLDNHEKITPMMRWRDAKKIIQDEEETFVKIASNSERKVERDFRD 823

  Fly  1033 YIKDKTMTAKTSLRELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHME-EERNTI 1096
            :.:.:........:|:|.|.|.|||||..|::|...|: :|..:|:||||::.:..|. .||:.:
 Worm   824 WQERRHDHLTDEFKEMLSETKIITHKSKKLMEEGEQHM-DILSVLENDKRWVRMTAMSASERDRM 887

  Fly  1097 VLGFLEELNKRGPPPPPTASESTRRNK 1123
            :...:|.|.::|.|||||..|..||.:
 Worm   888 LEDHIENLGRKGTPPPPTQQERDRRKQ 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42724	NP_001189184.1	WW	112..144	CDD:197736	15/31 (48%)
		Extensin_2	180..243	CDD:252669	5/62 (8%)
		WW	295..322	CDD:278809	13/26 (50%)
		WW	441..468	CDD:278809	21/26 (81%)
		FF	590..634	CDD:280090	28/43 (65%)
		FF	652..701	CDD:280090	21/48 (44%)
		FF	719..768	CDD:280090	15/49 (31%)
		FAT-like_CAS_C	871..>935	CDD:300863	18/63 (29%)
		FF	930..977	CDD:280090	16/46 (35%)
		FF	983..1036	CDD:128718	19/56 (34%)
		FF	1041..1096	CDD:280090	21/55 (38%)
tcer-1	NP_001370832.1	WW	168..195	CDD:197736	14/26 (54%)
		PRP40	235..>820	CDD:227435	236/743 (32%)
		FF	834..891	CDD:396424	21/57 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159576
Domainoid	1	1.000	57	1.000	Domainoid score	I7272
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	361	1.000	Inparanoid score	I1282
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52888
OrthoDB	1	1.010	-	-		D1388955at2759
OrthoFinder	1	1.000	-	-		FOG0002297
OrthoInspector	1	1.000	-	-		oto19137
orthoMCL	1	0.900	-	-		OOG6_103069
Panther	1	1.100	-	-	LDO	PTHR15377
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7471
SonicParanoid	1	1.000	-	-		X3901
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.940