Protein Alignment CG42724 and LOC1278480

DIOPT Version :10

• Sequence 1: NP_001189184.1
• Gene: CG42724 / 40785
• FlyBaseID: FBgn0261641
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_001689095.2
• Gene: LOC1278480 / 1278480
• VectorBaseID: AGAMI1_006084
• Length: 1081
• Species: Anopheles gambiae
• Alignment Length: 1183
• Identity: 571/1183 - (48%)
• Similarity: 731/1183 - (61%)
• Gaps: 195/1183 - (16%)

  Fly    20 KTEATESPPEAG-LNGNGSGSGSTSQETPNYGVAILKEKPSEAHRSKPFNAFSGRPIGEHTAQQQ 83
            :.|:||....|| ::|:...:.::.|.|          .||                    |...
Mosquito    12 EAESTEEVSNAGTIDGDSVVASASEQHT----------SPS--------------------AADS 46

  Fly    84 ALQQQQLQQQQQPQQPQQQAPSG-ANGVTGPPEIWVETKAEDGRSYYYHAVTRETTWSRPDGPAV 147
            .|::.::...:........|||. ||.|.  .::|||||..||:||||||::|||||:||:||.|
Mosquito    47 TLEENKVSPIKNGAGLLGSAPSKLANTVA--TDLWVETKTADGKSYYYHAISRETTWTRPEGPNV 109

  Fly   148 KIMTQAEVEEMAKRPAQAAKT--------EAKAGETSVEIPPVSSHLTSQPPPHLMSQPPPNAAA 204
            .:|||||||.:.|:..|...|        |..|...| :||..|:.:.:..|.|        .|.
Mosquito   110 NVMTQAEVEALNKQQQQQQHTKSAEQKVIEVNASSAS-DIPVSSATIPAVIPLH--------TAM 165

  Fly   205 PLLSQPPPNVRQQPPPMFQPPGMQAPPGFGQPPFCMPPPTY-GFPGGPAPA---GAPWGVG--IP 263
            ...:.|||:                   ||..||.||||.: .||....||   |..|.:|  :|
Mosquito   166 TRFTGPPPS-------------------FGMAPFGMPPPNFTSFPPWNPPAVGSGQNWSIGQTLP 211

  Fly   264 PWQQQQHMQDKPAKSLIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAGRGESVWEKPQALRDM 328
            ....:|.|.:       ||...|||:::|||..||||.|||||.:|::|.:|||||||||||||:
Mosquito   212 LDAAKQAMNE-------IKLNEIDPSIVARATVWSEHTAPDGRMFYYNASKGESVWEKPQALRDL 269

  Fly   329 EAARMAAHSGVAPAVATAPSGLPPHLLP-----NPM---MHMPPGSG------PPGFDPHAA--- 376
            |.|::...:  |...:.||..:||.|.|     .|:   |..||.:|      |   .|.|.
Mosquito   270 EKAKLTVWN--AKQKSKAPPSVPPFLAPPIPPQMPLMSAMQAPPATGLKIQQFP---SPLATAAI 329

  Fly   377 --------------FAAAAAAMKANSENTKAAQAAALEKEAKKAAEEKRKKEEEQKKAAASAKQT 427
                          .||:.......:...|..:|||.|:..:|..:||::||:|:|  |.|.|..
Mosquito   330 GPVSGSGVRLQQLPVAASGVVFDPITFMAKNEKAAAEEERKRKLEQEKKRKEDEEK--AKSNKPQ 392

  Fly   428 DKSRPVTSTPIAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQL---K 489
            |||||::||||:|||||||||||.||||||||||||||:|||:|..|.||||||...|:||   .
Mosquito   393 DKSRPISSTPISGTPWCVVWTGDGRVFFYNPSTRTSVWERPEELKERADVDKAVLVPPQQLLGTV 457

  Fly   490 TPQEKSAEAEQK------SGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVE 548
            .|:|.......|      :|..|....|:|       |..|  .|...:.:|....:::|||||:
Mosquito   458 APKELDGVTNSKGQTVLGTGNSATATLAES-------DGGQ--TASGGNTNEPRSAQSDSESSVD 513

  Fly   549 ---EVPTKRVR----MISKSKRA------------EDAALEAEQRAAKERALVPLEMRVTQFKEM 594
               |.|:|:::    .:.||..:            |..|:|||.|||:||.|:||::|:..|:||
Mosquito   514 EDGEHPSKKLKSDLEAVMKSTHSLGSNRSGTDPEKEAIAMEAEARAARERTLIPLDVRMKSFREM 578

  Fly   595 LREKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDFRS 659
            |||.||||||||||||||||:|.||||||||||||||||||||||:|||:||||||||||:|||:
Mosquito   579 LRELDVSAFSTWEKELHKIVYDARYLLLTSKERKQVFEKYVKDRADEERREKRNKMRQKRDDFRA 643

  Fly   660 LMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKEDKLLKKEQIRKDF 724
            ||:.|.||||||||||:|:..||||::.|||:|||||||||||||:|:||||:|.::||||||||
Mosquito   644 LMDAAHLHGKSSFSEFAQKYGKDERFKVIEKIRERESLFNEYIVEIRKREKEEKQIRKEQIRKDF 708

  Fly   725 LDMLRERHDIERHTRWYDIKKKFESDPRYRMV-DSMYREEYFEDYLHIMKEEKRKEREM---REQ 785
            |.|||||.||.||||:.||:||.|||.||:.: :...|||.|||::..:||||||.:|.   :|.
Mosquito   709 LTMLRERSDINRHTRFSDIRKKVESDSRYKAITEHSQREELFEDHIKALKEEKRKAKEKEREKEL 773

  Fly   786 RERERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSEK-SKKRDTT 849
            :||....|.:|.||.:|:.:|:      ||||.|:               |.|:|.| :...|.|
Mosquito   774 KERNSRSEQRSSRKSRDRSRDR------RSRSNDR---------------EASQSAKGASNHDGT 817

  Fly   850 PEEGEHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQRTLAGHLRD 914
              ...:.:|.|.|:...||:.|:.||        |:|||:|.|.|.||:|||||||||||.||||
Mosquito   818 --ANNNNDEDEGEDCNTSDEDEIERQ--------QRERERKARAEASIKEREKEVQRTLATHLRD 872

  Fly   915 RDKEREHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRERKFNEHID 979
            |||||:||.|:|.:.||.|||.||||..|.||||||:.|:||||||||..|||:||||.|||||.
Mosquito   873 RDKERQHHQRDEAMRHFNALLADLVRNADLTWKEVKKLLKKDHRWELISMLDRDDRERLFNEHIS 937

  Fly   980 NLMKKKRERFREMLDEISTLQLTSTWKEIKKLIKEDPRYLKYN-SDKGEREFRDYIKDKTMTAKT 1043
            ||::|||::||||||||.:|:|||:||:|||.|::|||||||| |::|||||||||||||..||.
Mosquito   938 NLVRKKRDKFREMLDEIPSLELTSSWKDIKKSIRDDPRYLKYNSSERGEREFRDYIKDKTANAKL 1002

  Fly  1044 SLRELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVLGFLEELNKRG 1108
            :.||||||||||||||.:|.:||.|||:|::|||:||.|||:|.|:..||..::|..||||:|||
Mosquito  1003 AFRELLQECKFITHKSFELYRENANHLREVEDILRNDSRYLILHHIAGERTQMILAHLEELHKRG 1067

  Fly  1109 PPPPPTASESTRR 1121
            ||||||||||.||
Mosquito  1068 PPPPPTASESLRR 1080

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42724	NP_001189184.1	WW	112..144	CDD:197736	20/31 (65%)
		PHA03247	<159..369	CDD:223021	79/237 (33%)
		Extensin_2	180..243	CDD:252669	14/62 (23%)
		WW	295..322	CDD:459800	17/26 (65%)
		PRP40	443..>753	CDD:227435	199/337 (59%)
		COG4913	<865..1105	CDD:443941	159/240 (66%)
		FF	930..977	CDD:426471	34/46 (74%)
		FF	983..1036	CDD:128718	39/53 (74%)
LOC1278480	XP_001689095.2	None