Protein Alignment CG42724 and tcerg1

DIOPT Version :10

• Sequence 1: NP_001189184.1
• Gene: CG42724 / 40785
• FlyBaseID: FBgn0261641
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_002935314.1
• Gene: tcerg1 / 100498472
• XenbaseID: XB-GENE-6258415
• Length: 1062
• Species: Xenopus tropicalis
• Alignment Length: 1129
• Identity: 409/1129 - (36%)
• Similarity: 575/1129 - (50%)
• Gaps: 306/1129 - (27%)

  Fly   102 QAPSGANGVTGPP--EIWVETKAEDGRSYYYHAVTRETTWSRPDGPAVKIMTQAEVEEM--AKRP 162
            |:|:.....|.||  |||||.|..||:.|||:|.|||:.||:|||  ||::.|:|:..:  |:..
 Frog   130 QSPTPTQAPTLPPNEEIWVENKTPDGKVYYYNARTRESAWSKPDG--VKVIQQSELTPLMAAQAQ 192

  Fly   163 AQAAKTEAKAGETSVE------------------------------------------IPPVSSH 185
            ||||:.:|:|.:...:                                          :.|.|:.
 Frog   193 AQAAQAQAQAAQAQAQAQAQAAQVQVAQAQGQVQVAHSQPIHSQTVTGASTTTTSTSMLVPTSTP 257

  Fly   186 LTSQ------PPPHLMSQPPPNAAAP------LLSQP---------------------PPNVRQQ 217
            .|||      ...:.:||..|:::||      .:|.|                     |..:.|.
 Frog   258 STSQASSTNTTTSNSISQAIPSSSAPEHTQTQSVSAPVTVSSVSVATSLPTVSSVQSLPAQLSQV 322

  Fly   218 PPPMFQ---PPGMQAPPGFGQPPFCMPPPTYGFPGGPAP---------AGAPW---------GV- 260
            .||...   |....|.|.|  ||..:||.....||.|.|         ...|:         ||
 Frog   323 LPPTVSHAVPQPAAAIPAF--PPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVL 385

  Fly   261 -GI-PPWQQQQHMQDKPAKSLIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAGRGESVWEKPQ 323
             || ||.....|    |..:|...|..:..|.|  .:||||::..||:.||::....||.|:||.
 Frog   386 PGIAPPIVPMIH----PQVALAASPATLAGATI--LSEWSEYKTADGKTYYYNNRTLESTWDKPH 444

  Fly   324 AL--RDMEAARMAAHSGVAPAVATAPSGLPPHLLPNPMMHMPPGSGPPGFDPHAAFAAAAAAMKA 386
            .|  :|.|..::...:...|.:.....       |...|...|...||
 Frog   445 ELKEKDKEIEKVKESTKPEPVIKEDAQ-------PMEAMEDIPKEEPP----------------- 485

  Fly   387 NSENTKAAQAAALEKEAKKAAEEKRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVVWTGDS 451
                          ||.|:..:|:...|||        |...|:|||.:|||.|||||||||||.
 Frog   486 --------------KEIKEEVKEEEMTEEE--------KAAQKARPVATTPIPGTPWCVVWTGDE 528

  Fly   452 RVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQ 516
            |||||||:||.|:|||||||:.|.||||.:.|.|              .|.|.|..::..|....
 Frog   529 RVFFYNPTTRLSMWDRPEDLIGRADVDKIIQEPP--------------HKRGMEDGKKYYKEDQD 579

  Fly   517 AQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERAL 581
            :          |:|.::||.||.:...:...|              ..::.|:|||.:||:|||:
 Frog   580 S----------AEDANEDEPIKAKKRKKDDPE--------------ADKETAMEAEIKAARERAI 620

  Fly   582 VPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEK 646
            |||:.|:.||::||.|:.|||||||||||||||||||||||..|||||||::|||.||||||:||
 Frog   621 VPLDSRMKQFRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREK 685

  Fly   647 RNKMRQKREDFRSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKE 711
            :||:.|.:|||:.:||:.:::.:|:||||:.::|||.|::||||:::||:|||||:|..|::|||
 Frog   686 KNKIMQAKEDFKKMMEDGKINARSTFSEFAGKHAKDARFKAIEKMKDRETLFNEYMVAARKKEKE 750

  Fly   712 DKLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRYRMVD-SMYREEYFEDYLHIMKEE 775
            |...|.|::|.||.|:|...| ::..:||..||.|.|:|.||:.|: |..|||.|:.|:
 Frog   751 DSKNKGEKVRSDFFDLLSSLH-LDGQSRWSKIKDKIENDLRYKAVESSAAREELFKLYI------ 808

  Fly   776 KRKEREMREQRERERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKS 840
                                                            .|..|..|.:||
 Frog   809 ------------------------------------------------EKIVKNLDTEKE----- 820

  Fly   841 EKSKKRDTTPEEGEHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQ 905
                                                        ||.|::.|:|.|:||||:|||
 Frog   821 --------------------------------------------KELERQARIEASLREREREVQ 841

  Fly   906 RTLAGHLRDRDKEREHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDR 970
            :..:...::.|:|||.|.|||.|.:|.|||:|:||:.|.:|.:.:|.||||||||....|:||::
 Frog   842 KARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEK 906

  Fly   971 ERKFNEHIDNLMKKKRERFREMLDEISTLQLTSTWKEIKKLIKEDPRYLKYNSD--KGEREFRDY 1033
            |:.|:|||:.|.|||||:||::|||...:.|||||||:||:||:|||.:|::|.  |.:|||.:|
 Frog   907 EKLFSEHIEALTKKKREQFRQLLDETCAITLTSTWKEVKKIIKDDPRCIKFSSSDRKKQREFEEY 971

  Fly  1034 IKDKTMTAKTSLRELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVL 1098
            |:||.:|||...|.||:|.||||::|...::|:..|||:::.||:|||||||||.:.|||..:::
 Frog   972 IRDKHITAKADFRTLLKETKFITYRSKKFLQESDQHLKDVEKILQNDKRYLVLDCIPEERRKLIM 1036

  Fly  1099 GFLEELNKRGPPPPPTASESTRRN 1122
            .::::|::|||||||||||..||:
 Frog  1037 SYVDDLDRRGPPPPPTASEPARRS 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42724	NP_001189184.1	WW	112..144	CDD:197736	20/33 (61%)
		PHA03247	<159..369	CDD:223021	68/310 (22%)
		Extensin_2	180..243	CDD:252669	23/98 (23%)
		WW	295..322	CDD:459800	11/26 (42%)
		PRP40	443..>753	CDD:227435	151/309 (49%)
		COG4913	<865..1105	CDD:443941	113/241 (47%)
		FF	930..977	CDD:426471	23/46 (50%)
		FF	983..1036	CDD:128718	32/54 (59%)
tcerg1	XP_002935314.1	PLN02983	<92..>138	CDD:215533	2/7 (29%)
		WW	140..172	CDD:459800	19/31 (61%)
		PRP40	404..982	CDD:227435	294/767 (38%)
		FF	979..1038	CDD:426471	29/58 (50%)