Protein Alignment Hr83 and PPARA

DIOPT Version :9

• Sequence 1: NP_649647.1
• Gene: Hr83 / 40783
• FlyBaseID: FBgn0037436
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_001001928.1
• Gene: PPARA / 5465
• HGNCID: 9232
• Length: 468
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 81/380 - (21%)
• Similarity: 146/380 - (38%)
• Gaps: 126/380 - (33%)

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALV-----GNCVVDKARRNWCPSCRFQ 66
            |.:|||::||.||||..|:||..||:|::|       :.||     .:|.:.|..||.|..|||.
Human   102 CRICGDKASGYHYGVHACEGCKGFFRRTIR-------LKLVYDKCDRSCKIQKKNRNKCQYCRFH 159

  Fly    67 RCLAVGMNAAAVQEERGPRNQQVAL---YRTGRRQAPPSQAAPSPTPHSQALHF--------QIL 120
            :||:|||:..|::..|.||:::..|   ..|.......|:.|...:...:....        ::.
Human   160 KCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVK 224

  Fly   121 AQILVT-----------------CLRQ-------------------------------------- 130
            |:::::                 |:.:
Human   225 ARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTE 289

  Fly   131 -AKANEQFALLDRCQQDAIFQV-VWSEIFVLRASHWSLDISAMIDGCGD--------EQLKRLIC 185
             |||...||.||...|..:.:. |:..||.:.:|..:.|  .|:...|:        :.|::..|
Human   290 FAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKD--GMLVAYGNGFITREFLKSLRKPFC 352

  Fly   186 EAHQ------LRADVLELN------FMESLILC--RKELAINAEYAVILGSHSKAALISLARYTL 236
            :..:      ::.:.|||:      |:.::|.|  |..| :|..:.    ...:..::.:.|..|
Human   353 DIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGL-LNVGHI----EKMQEGIVHVLRLHL 412

  Fly   237 QQSN------YLRFGQLLLGLRQLCLR-----------RFDCALSCMFRSVVRDI 274
            |.::      :.:..|.:..||||...           ..|.||..:.:.:.||:
Human   413 QSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDM 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	36/85 (42%)
PPARA	NP_001001928.1	NR_DBD_Ppar	101..184	CDD:143523	36/88 (41%)
		NR_LBD_PPAR	201..467	CDD:132730	41/272 (15%)
		Required for heterodimerization with RXRA	304..433		23/135 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910