DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr83 and rxrgb

DIOPT Version :9

Sequence 1:	NP_649647.1	Gene:	Hr83 / 40783	FlyBaseID:	FBgn0037436	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	XP_005160723.1	Gene:	rxrgb / 436617	ZFINID:	ZDB-GENE-040718-34	Length:	465	Species:	Danio rerio

Alignment Length:	317	Identity:	92/317 - (29%)
Similarity:	136/317 - (42%)	Gaps:	60/317 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            ||:|||:||||||||..|:||..||||::|:..:|.| ..:..|::||.:||.|..||:|:|||:
Zfish   141 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYTC-RDIKECLIDKRQRNRCQYCRYQKCLAM 204

  Fly    72 GMNAAAVQEE--RGPRNQQVALYRTGR------------------------RQAPPSQAAPSP-T 109
            ||...|||||  ||.......:..|.|                        .::.||.:...| |
Zfish   205 GMKREAVQEERQRGKEKSDTEVETTSRFNEDMPVDKILDAELSVEPKTETYTESSPSNSTNDPVT 269

  Fly   110 PHSQALHFQILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWSLDI------ 168
            ....|...|     |.|.:..||....|:.|....|..:.:..|:|:.:...||.|:.:
Zfish   270 NICHAADKQ-----LFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSITVKDGILL 329

  Fly   169 ---------SAMIDGCG---DEQLKRLICEAHQLRADVLELNFMESLILCR---KELAINAEYAV 218
                     ||...|.|   :..|..|:.:...::.|..||..:.:::|..   |.|:.:.|...
Zfish   330 GTGLHVHRSSAHSAGVGSIFNRVLTELVSKMKDMQMDKTELGCLRAIVLFNPDAKGLSNSLEVEA 394

  Fly   219 ILGSHSKAALISLARYTLQQ--SNYLRFGQLLLGLRQLCLRRFDCALSCMFRSVVRD 273
            :    .:....||..||.|:  ....||.:|||.|..|......|.....|..::.|
Zfish   395 L----REKVYASLETYTKQKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	44/82 (54%)
rxrgb	XP_005160723.1	Nuc_recep-AF1	30..135	CDD:288658
		NR_DBD_RXR	139..215	CDD:143514	41/74 (55%)
		NR_LBD_RXR_like	235..443	CDD:132741	45/216 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577476
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840