DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr83 and nr2f1b

DIOPT Version :9

Sequence 1:	NP_649647.1	Gene:	Hr83 / 40783	FlyBaseID:	FBgn0037436	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_956886.1	Gene:	nr2f1b / 393564	ZFINID:	ZDB-GENE-040426-1438	Length:	389	Species:	Danio rerio

Alignment Length:	298	Identity:	93/298 - (31%)
Similarity:	136/298 - (45%)	Gaps:	56/298 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            |.||||:|||||||...|:||..||||||||..||.|.| ..||.||:..||.|..||.::||.|
Zfish    54 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRA-NRNCPVDQHHRNQCQYCRLKKCLKV 117

  Fly    72 GMNAAAVQEERGPRNQ----QVAL----------YRTG----RRQAPPSQAAPSPTPHSQALHF- 117
            ||...|||..|.|.||    ..||          |.:|    ..:|.|..|:.......|:.:.
Zfish   118 GMRREAVQRGRMPPNQPNPSHYALTNGDHLNGQCYLSGYISLLLRAEPYPASRYGNQCMQSGNIM 182

  Fly   118 ------QILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWS--LDISAMIDG 174
                  ::.|::|.:.:..|:....|..|....|.::.::.|||:|||.|:..|  |.::.::..
Zfish   183 GIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQSSMPLHVAPLLAA 247

  Fly   175 CG---------------------DEQLKRLICEAHQLRADVLELNFMESLILCRKELAINAEYAV 218
            .|                     .||:::|    ..|:.|..|.:..::::|...:....::...
Zfish   248 AGLHASPMSADRVVAFMDHIRFFQEQVEKL----KALQVDSAEYSCAKAIVLFTSDACGLSDIPH 308

  Fly   219 ILGSHSKAALISLARYTLQQ--SNYLRFGQLLLGLRQL 254
            |.|...|:. .:|..|...|  :...|||:|||.|..|
Zfish   309 IEGLQEKSQ-CALEEYVRSQYPNQPTRFGKLLLRLPAL 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	48/84 (57%)
nr2f1b	NP_956886.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..39
		NR_DBD_COUP_TF	54..126	CDD:143516	43/72 (60%)
		NR_LBD_COUP-TF	152..387	CDD:132746	43/199 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840