Protein Alignment Hr83 and HNF4G

DIOPT Version :10

• Sequence 1: NP_649647.1
• Gene: Hr83 / 40783
• FlyBaseID: FBgn0037436
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_004124.5
• Gene: HNF4G / 3174
• HGNCID: 5026
• Length: 455
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 81/288 - (28%)
• Similarity: 122/288 - (42%)
• Gaps: 44/288 - (15%)

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            ||:|||:::|||||.|.||||..||:||:|:...|:| .....|||||.:||.|..||.::|...
Human    59 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSC-RFSRQCVVDKDKRNQCRYCRLRKCFRA 122

  Fly    72 GMNAAAVQEERG--------------PRNQQVALYRTGRRQAPPSQAAPSPTPHSQALH-----F 117
            ||...|||.||.              |....:|......||...|....|...:.:.:.     .
Human   123 GMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVC 187

  Fly   118 QILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWSLDISAMIDGCGDEQLKR 182
            :.:.|.|:..:..||....|..|....|.|:.:....|..:|.|:..|:....::....:..:.|
Human   188 ESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHR 252

  Fly   183 LICEAHQLRADVLELNFMESLILCRKELAI-NAEYAVILG---------SHSKAALISLARYTLQ 237
            ..||....|   :....::.|:...:|:.| :.|||.:..         ..|....|...|:.:|
Human   253 NSCEVEISR---VANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQ 314

  Fly   238 --QSNYL---------RFGQLLLGLRQL 254
              ..:|:         |||:|||.|..|
Human   315 IGLEDYINDRQYDSRGRFGELLLLLPTL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	41/94 (44%)
HNF4G	NP_004124.5	NR_DBD_HNF4A	59..134	CDD:143518	39/75 (52%)
		NR_LBD_HNF4_like	150..371	CDD:132729	40/196 (20%)