DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr83 and nr2f5

DIOPT Version :9

Sequence 1:	NP_649647.1	Gene:	Hr83 / 40783	FlyBaseID:	FBgn0037436	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_571261.1	Gene:	nr2f5 / 30427	ZFINID:	ZDB-GENE-990415-253	Length:	403	Species:	Danio rerio

Alignment Length:	313	Identity:	96/313 - (30%)
Similarity:	134/313 - (42%)	Gaps:	86/313 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGN--CVVDKARRNWCPSCRFQRCL 69
            |.||||:|||||||...|:||..||||||||..||.|   .||  |.:|:..||.|..||.::||
Zfish    54 CMVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTC---RGNRDCPIDQHHRNQCQYCRLKKCL 115

  Fly    70 AVGMNAAAVQEERGPRNQQVALYRTGRRQAPPSQ------------------------AAPSPTP 110
            .|||...|||  ||         |....|:.|.|                        |.|.||.
Zfish   116 KVGMRREAVQ--RG---------RMSNSQSSPGQYLSNGSDPYNGQPYLSGFISLLLRAEPYPTS 169

  Fly   111 HSQALHFQ------------ILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASH 163
            ...|...|            :.|::|.:.:..||....|..|....|.|:.::.|||:|||.|:.
Zfish   170 RYGAQCMQSNNLMGIENICELAARLLFSAVEWAKNIPFFPDLQLMDQVALLRMSWSELFVLNAAQ 234

  Fly   164 WS--LDISAMIDGCG---------------------DEQLKRLICEAHQLRADVLELNFMESLIL 205
            .|  |.::.::...|                     .||:::|    ..|:.|..|.:.::|::|
Zfish   235 CSMPLHVAPLLAAAGLHASPMSAERVVAFMDHIRVFQEQVEKL----KALQVDTAEYSCLKSIVL 295

  Fly   206 CRKELAINAEYAVI--LGSHSKAALISLAR--YTLQQSNYLRFGQLLLGLRQL 254
            ...:....::.|.:  :...|:.||....|  |..|.:   |||:|||.|..|
Zfish   296 FTSDAMGLSDVAHVESIQEKSQCALEEYVRNQYPNQPN---RFGRLLLRLPSL 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	45/82 (55%)
nr2f5	NP_571261.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..44
		NR_DBD_COUP_TF	54..126	CDD:143516	43/76 (57%)
		NR_LBD_COUP-TF	152..387	CDD:132746	47/201 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840