Protein Alignment Hr83 and NR2F6

DIOPT Version :9

• Sequence 1: NP_649647.1
• Gene: Hr83 / 40783
• FlyBaseID: FBgn0037436
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_005225.2
• Gene: NR2F6 / 2063
• HGNCID: 7977
• Length: 404
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 95/355 - (26%)
• Similarity: 145/355 - (40%)
• Gaps: 106/355 - (29%)

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            |.||||:||||||||..|:||..|||||:||..||.|.: ..:|.:|:..||.|..||.::|..|
Human    56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRS-NRDCQIDQHHRNQCQYCRLKKCFRV 119

  Fly    72 GMNAAAVQEERGPRNQQVALYRTGRRQAPPSQAAPSPTPHSQAL--------------------- 115
            ||...|||..|.|.:            .|.:.||.|.:|...||
Human   120 GMRKEAVQRGRIPHS------------LPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQ 172

  Fly   116 ------------HF-----------------QILAQILVTCLRQAKANEQFALLDRCQQDAIFQV 151
                        .|                 ::.|::|.:.:..|:....|..|....|.|:.::
Human   173 LLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRL 237

  Fly   152 VWSEIFVLRASHWSLDI--SAMIDGCG---------------------DEQLKRLICEAHQLRAD 193
            .|||:|||.|:..:|.:  :.::...|                     .||:.:|    .:|:.|
Human   238 SWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKL----GRLQVD 298

  Fly   194 VLELNFMESLILCRKELAINAEYAVILGSHSKAALISLARYTLQQ--SNYLRFGQLLLGLRQLCL 256
            ..|...::::.|...:....::.|.:.....||. ::|..|...|  |...|||:||  ||...|
Human   299 SAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ-VALTEYVRAQYPSQPQRFGRLL--LRLPAL 360

  Fly   257 RRFDCAL-SCMF----------RSVVRDIL 275
            |....:| |.:|          .:::||:|
Human   361 RAVPASLISQLFFMRLVGKTPIETLIRDML 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	42/80 (53%)
NR2F6	NP_005225.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49
		NR_DBD_COUP_TF	56..128	CDD:143516	39/72 (54%)
		NR_LBD_COUP-TF	165..400	CDD:132746	46/233 (20%)
		Important for dimerization. /evidence=ECO:0000250	327..404		21/67 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144379
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840