DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr83 and Rxrg

DIOPT Version :9

Sequence 1:	NP_649647.1	Gene:	Hr83 / 40783	FlyBaseID:	FBgn0037436	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_033133.1	Gene:	Rxrg / 20183	MGIID:	98216	Length:	463	Species:	Mus musculus

Alignment Length:	318	Identity:	87/318 - (27%)
Similarity:	137/318 - (43%)	Gaps:	62/318 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            ||:|||:||||||||..|:||..||||::|:...|.| ....:|::||.:||.|..||:|:||.:
Mouse   139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTC-RDNKDCLIDKRQRNRCQYCRYQKCLVM 202

  Fly    72 GMNAAAVQEERGPRNQQVALYRTGRRQAPPSQAAPSPTPHSQALHFQILAQ-------------- 122
            ||...|||||| .|:::.|     ..:|..:.::....|..:.|..::..:
Mouse   203 GMKREAVQEER-QRSRERA-----ESEAECASSSHEDMPVERILEAELAVEPKTESYGDMNVENS 261

  Fly   123 --------------ILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWSLDI----- 168
                          .|.|.:..||....|:.|....|..:.:..|:|:.:...||.|:.:
Mouse   262 TNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGIL 326

  Fly   169 ----------SAMIDGCG---DEQLKRLICEAHQLRADVLELNFMESLILCR---KELAINAEYA 217
                      ||...|.|   |..|..|:.:...::.|..||..:.:::|..   |.|:..:|..
Mouse   327 LATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVE 391

  Fly   218 VILGSHSKAALISLARYTLQQ--SNYLRFGQLLLGLRQLCLRRFDCALSCMFRSVVRD 273
            .:    .:....:|..||.|:  ....||.:|||.|..|......|.....|..::.|
Mouse   392 TL----REKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	43/80 (54%)
Rxrg	NP_033133.1	Modulating. /evidence=ECO:0000250	1..138
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..53
		Nuc_recep-AF1	25..133	CDD:288658
		NR_DBD_RXR	137..213	CDD:143514	40/74 (54%)
		Hinge	205..230		9/30 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..232		6/26 (23%)
		NR_LBD_RXR_like	233..441	CDD:132741	41/211 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840