Protein Alignment Hr83 and nhr-69

DIOPT Version :10

• Sequence 1: NP_649647.1
• Gene: Hr83 / 40783
• FlyBaseID: FBgn0037436
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_492615.2
• Gene: nhr-69 / 172840
• WormBaseID: WBGene00003659
• Length: 373
• Species: Caenorhabditis elegans
• Alignment Length: 337
• Identity: 83/337 - (24%)
• Similarity: 138/337 - (40%)
• Gaps: 89/337 - (26%)

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            |.:|.|:|:|||||...||||..||:||:|:...|.| ....||.|.|.:||.|.:||.|:|:..
 Worm     6 CHICNDKSTGKHYGAISCDGCKGFFRRSIRKRYHYQC-RFEQNCDVTKNKRNACRACRLQKCVKA 69

  Fly    72 GMNAAAVQEER---GPRNQ-----------QVALYRTGRRQAPPS--QAAPSPTPH--------- 111
            ||.:.|:|.||   |.|.:           |:....|..:|...|  :...|..|:
 Worm    70 GMKSNAIQNERDAIGKRKKTTGAEKEDLIDQLVAAETLCQQLRSSVIKNTSSLAPYDCGKVKWNY 134

  Fly   112 -----------SQALHFQILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWS 165
                       .:::|     |.||..:..||:..||:.|.:..|.|:.:...:.|.||..::.|
 Worm   135 EDARAATLDDIGKSIH-----QQLVLFIEWAKSLPQFSFLAQADQAALLKGGAASIIVLGVAYRS 194

  Fly   166 L-------------------------DISAMIDGCGDEQLKRLICEAHQLRADVLELNFMESLIL 205
            :                         ||:.::....||    ::....:|..|::|...:::::.
 Worm   195 ICLTVENTICLANDTLLPKEHATQVGDINCVVGRIIDE----IVNPMRRLNMDLIEYVALKAILF 255

  Fly   206 CR---KEL-----AINAEYAVILGSHSKAALISLARYTLQQSNYLRFGQLLLGLRQLCLRRFDCA 262
            ..   :|:     ..||.||.:.....:....:|.... .:|...|.|:|||.|.         :
 Worm   256 FNPVVREINDQSPVENARYAFLRSLQRRCTDKALENME-DESMDCRSGKLLLLLP---------S 310

  Fly   263 LSCMFRSVVRDI 274
            |..:.:.:|.|:
 Worm   311 LQAIAQQLVEDV 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	39/94 (41%)
nhr-69	NP_492615.2	NR_DBD_HNF4A	6..81	CDD:143518	36/75 (48%)
		NR_LBD	98..340	CDD:472173	44/244 (18%)