Protein Alignment Hr83 and nhr-64

DIOPT Version :10

• Sequence 1: NP_649647.1
• Gene: Hr83 / 40783
• FlyBaseID: FBgn0037436
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_001343721.1
• Gene: nhr-64 / 171884
• WormBaseID: WBGene00003654
• Length: 375
• Species: Caenorhabditis elegans
• Alignment Length: 330
• Identity: 90/330 - (27%)
• Similarity: 133/330 - (40%)
• Gaps: 88/330 - (26%)

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            ||:|||:::|||||...||||..||:|::|:..||.| .....|.||||:||.|..|||..||..
 Worm    33 CAICGDRATGKHYGAMSCDGCKGFFRRTIRKRHSYVC-RFGEKCQVDKAKRNSCRKCRFDVCLRK 96

  Fly    72 GMNAAAVQEE-----------------------------------RGPRNQQVALYRTGRRQAPP 101
            ||...|||.|                                   ||.|...:......|:||..
 Worm    97 GMRRDAVQTERDRIRPANPLSNGSNGGIVPDDPLLDTLIRAEASTRGLRTTVITKTAEARKQATT 161

  Fly   102 SQAAPSPTPHSQALHFQILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWSL 166
            :....|            :.|.|...:..||..|.|..:|...|.|:.:...::..|:.|:..|:
 Worm   162 NDVTDS------------MNQQLTLMVEWAKVLEGFQRVDNITQVALLRHFSAQHLVMCAAFRSI 214

  Fly   167 DISAMI----DGC----------GDEQLKRLICE-AHQLRADVLELNFMESLILCRKELAINAEY 216
            .:|..:    :.|          .:...:|:|.: .:.:|:  |.:|.:|.:.|  |.:|.....
 Worm   215 HLSDAVWLTNETCLHKDSPKIPDMNRVAERIIDQVTNPMRS--LHMNEIEYIAL--KAIAFFDPL 275

  Fly   217 AVILGSHS--------KAALISLARYTLQQSNY----LRFGQLLLGLRQLCLRRFDCALSCMFRS 269
            |..:.|.|        :..|.|..|:....|.|    |||..|||.|..:      .|:|   |.
 Worm   276 AKGITSESYSDVEEMRQRILESFERHVRYVSPYKDMPLRFANLLLLLPPM------LAIS---RD 331

  Fly   270 VVRDI 274
            :|.|:
 Worm   332 LVEDV 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	43/115 (37%)
nhr-64	NP_001343721.1	NR_DBD_HNF4A	33..108	CDD:143518	40/75 (53%)
		NR_LBD	132..354	CDD:472173	50/230 (22%)