DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr83 and Nr2f6

DIOPT Version :9

Sequence 1:	NP_649647.1	Gene:	Hr83 / 40783	FlyBaseID:	FBgn0037436	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_034280.2	Gene:	Nr2f6 / 13864	MGIID:	1352453	Length:	390	Species:	Mus musculus

Alignment Length:	342	Identity:	96/342 - (28%)
Similarity:	144/342 - (42%)	Gaps:	94/342 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAV 71
            |.||||:||||||||..|:||..|||||:||..||.|.: ..:|.:|:..||.|..||.::|..|
Mouse    57 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRS-NRDCQIDQHHRNQCQYCRLKKCFRV 120

  Fly    72 GMNAAAVQEERGPRNQQVALYRTGRRQAPPSQAAPSP------------------------TPHS 112
            ||...|||..|.|             .|.|..||.||                        .|:.
Mouse   121 GMRKEAVQRGRIP-------------HALPGPAACSPPGATGVEPFTGPPVSELIAQLLRAEPYP 172

  Fly   113 QALHF-------------QILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHW 164
            .|..|             ::.|::|.:.:..|:....|..|....|.|:.::.|||:|||.|:..
Mouse   173 AAGRFGGGGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPAADQVALLRLSWSELFVLNAAQA 237

  Fly   165 SLDI--SAMIDGCG---------------------DEQLKRLICEAHQLRADVLELNFMESLILC 206
            :|.:  :.::...|                     .||:.:|    .:|:.|..|...::::.|.
Mouse   238 ALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKL----GRLQVDAAEYGCLKAIALF 298

  Fly   207 RKELAINAEYAVILGSHSKAALISLARYTLQQ--SNYLRFGQLLLGLRQLCLRRFDCAL-SCMF- 267
            ..:....::.|.:.....||. ::|..|...|  |...|||:||  ||...||....:| |.:|
Mouse   299 TPDACGLSDPAHVESLQEKAQ-VALTEYVRAQYPSQPQRFGRLL--LRLPALRAVPASLISQLFF 360

  Fly   268 ---------RSVVRDIL 275
                     .:::||:|
Mouse   361 MRLVGKTPIETLIRDML 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr83	NP_649647.1	NR_DBD_PNR_like_2	7..88	CDD:143515	42/80 (53%)
Nr2f6	NP_034280.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50
		NR_DBD_COUP_TF	57..129	CDD:143516	39/72 (54%)
		NR_LBD_COUP-TF	157..387	CDD:132746	48/228 (21%)
		Important for dimerization. /evidence=ECO:0000250	314..390		21/67 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840