DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Znrf3 and meu34

DIOPT Version :9

Sequence 1:	NP_001074393.1	Gene:	Znrf3 / 407821	MGIID:	3039616	Length:	913	Species:	Mus musculus
Sequence 2:	NP_593329.1	Gene:	meu34 / 2543036	PomBaseID:	SPAC3A12.03c	Length:	309	Species:	Schizosaccharomyces pombe

Alignment Length:	162	Identity:	38/162 - (23%)
Similarity:	54/162 - (33%)	Gaps:	61/162 - (37%)

- Green bases have known domain annotations that are detailed below.

Mouse   232 ILLVKIKLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDT--------------- 281
            :|...|..::|||..|...|:..:|| :...|:..|.||..:|....||.
pombe    89 VLGYDIPSRRRRSVVSKEALSCISLE-IPYIKWLKKRKGHAKGESTFLDNRSENQSVIVQGQGET 152

Mouse   282 ---------------------------------LSSGSTSD-----------CAICLEKYIDGEE 302
                                             .|.|.:||           |.||...|...:.
pombe   153 PSVIITYDVRRPNLGSTSFVEMSSALSNIYNTDASDGDSSDDSCLLEDEEDFCIICYADYAFDDI 217

Mouse   303 LRVIPCTHRFHRKCVDPWL-LQHHTCPHCRHN 333
            |||:||.|.||.:|:|.|: ....:||.|..:
pombe   218 LRVLPCEHVFHTQCIDTWMTTMKASCPLCNED 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Znrf3	NP_001074393.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		zf-RING_2	289..331	CDD:290367	18/53 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	601..669
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	855..913
meu34	NP_593329.1	RING	205..249	CDD:238093	18/43 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	59	1.000	Domainoid score	I3398
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm59359
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R768
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030