Protein Alignment CG18048 and TRMT13

DIOPT Version :9

• Sequence 1: NP_649646.3
• Gene: CG18048 / 40782
• FlyBaseID: FBgn0037435
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_061956.2
• Gene: TRMT13 / 54482
• HGNCID: 25502
• Length: 481
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 147/483 - (30%)
• Similarity: 249/483 - (51%)
• Gaps: 82/483 - (16%)

  Fly    16 PVTTTCSYWVLRKKRRCKMTANKGSEFCGAHASSAATTATCDEKAREDSFQERIPCPLDHKHTVF 80
            |....|.|:|.:|||.|:|....|..|||.||.:          |.|:..::||.||||.||||:
Human    14 PAEGRCGYYVEKKKRFCRMVVAAGKRFCGEHAGA----------AEEEDARKRILCPLDPKHTVY 68

  Fly    81 KRKLAKHLTICNARDQESSLPYIVKGVNSGDNLKETDEDLNKFNQIKLHELADEEFYSLIDKVKN 145
            :.:|||||..||:|::... .:.::.:|:|  |::..|...:.  :.:..|::|:...||.|::.
Human    69 EDQLAKHLKKCNSREKPKP-DFYIQDINAG--LRDETEIPEQL--VPISSLSEEQLEKLIKKLRK 128

  Fly   146 LYDKHINSSIQELQLEHESLKEELSRKDYGQETLRQLTQTTSLLGILEHDHQLMDHTSYIEFGAG 210
            . .:.:||::::..:.|.:|.:.|:....|....:.|.|..|:||.:|:...|.....::|||||
Human   129 A-SEGLNSTLKDHIMSHPALHDALNDPKNGDSATKHLKQQASILGNIENLKLLGPRRCFVEFGAG 192

  Fly   211 KGQLAYFLATVLQEQKLSHSQVVLIDRMSLRHKKDNKLANR-EVVQRIRADIADLKLSALPELKK 274
            ||:|::::...|::.:..|  .:|:::::.|.|.|.|...: .|.:|::.||..|.|:.:|.|::
Human   193 KGKLSHWVDIALKDAEKVH--FILVEKVTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLRE 255

  Fly   275 TQ-RTVAFSKHLCGAATDLTLRCILGDGNASSDY------------------------------- 307
            .: ..|...|||||.||||.|||::....||.:.
Human   256 EKLPVVGIGKHLCGMATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNV 320

  Fly   308 ---------VLIALCCHHRCSWRSYVGRKFLQEAGIGPREFVILTKMVSWAVCG-------TGLS 356
                     ::|||||||||.||.|||:::.:..|:|..||....:|.|||.||       |..|
Human   321 PEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSLETSNS 385

  Fly   357 RERRKAMESADFQLTETNTQRLTR------------QEREQIGQQCKRVLDYGRLEHLRSHGYQA 409
            ..:|:..::.|.:..:....|:|.            :|:::||..||.::|.||:::|:..|:..
Human   386 TTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEEKKKIGHLCKLLIDQGRIQYLQQKGFSP 450

  Fly   410 ELKFYVPRDVTLENVVLLARP---TSPK 434
            .|::|....|:||||:|.|.|   :||:
Human   451 ALQYYTDPLVSLENVLLTALPNHSSSPE 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18048	NP_649646.3	zf-TRM13_CCCH	20..44	CDD:288558	10/23 (43%)
		zf-U11-48K	69..92	CDD:283028	14/22 (64%)
		TRM13	183..429	CDD:282990	92/306 (30%)
TRMT13	NP_061956.2	zf-TRM13_CCCH	17..45	CDD:288558	12/27 (44%)
		zf-U11-48K	59..80	CDD:283028	13/20 (65%)
		TRM13	165..469	CDD:282990	92/305 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..408		5/26 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158293
Domainoid	1	1.000	146	1.000	Domainoid score	I4540
eggNOG	1	0.900	-	-		E1_KOG2811
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6875
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3438
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54880
OrthoDB	1	1.010	-	-		D364329at33208
OrthoFinder	1	1.000	-	-		FOG0005014
OrthoInspector	1	1.000	-	-		oto90148
orthoMCL	1	0.900	-	-		OOG6_103381
Panther	1	1.100	-	-	LDO	PTHR12998
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1546
SonicParanoid	1	1.000	-	-		X3545
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800