DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Osi17 and Osi21

DIOPT Version :9

Sequence 1:	NP_001262307.1	Gene:	Osi17 / 40774	FlyBaseID:	FBgn0037427	Length:	750	Species:	Drosophila melanogaster
Sequence 2:	NP_609501.1	Gene:	Osi21 / 34566	FlyBaseID:	FBgn0283678	Length:	282	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	81/374 - (21%)
Similarity:	111/374 - (29%)	Gaps:	163/374 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LIFLLLICLINSAAKADGTARNGRLGRHLSTTPLSHPTVESQPTEEQEMFTESPTESPEDVELAT 107
            |.:|||:.|:.|.:.| .|.|..|           |..|||           :.|.||.|  ..|
  Fly     4 LEWLLLLALVASVSTA-VTPRRRR-----------HSAVES-----------ATTSSPGD--WGT 43

  Fly   108 TTELPPEEDWQPLINATKFPTRKPMDKMAPSDSLLLRLARRFASGNELWDGLVRDCYLKPD-VSC 171
            ...|.||                            :.|.||      ::|    ||..|.| :.|
  Fly    44 AWGLGPE----------------------------MALVRR------VYD----DCQDKNDFIGC 70

  Fly   172 FQKNVFSYLDNVLDVQDVNVTQRLKFFKNQVDYQVDKEKEEHSE----------ARAASAETPIE 226
            .::.....|...||...:.:...|..           ||:..||          ||.....:||:
  Fly    71 LKQKALHALSRALDQDSIKIVDGLAL-----------EKQNQSETESILGSLTDARQFGNLSPID 124

  Fly   227 EVTSALYGKSIKFAMTHDLEVDLPEVMFNGATFRI-------SPRAIEGNGIIAKLELIPKQVVK 284
            .   ||..|:.|...||.|::|:.   ..|....:       ..:..||..|        |.||.
  Fly   125 R---ALLSKADKLMRTHTLKIDMD---VGGGEDSVGREHGHKKKKHKEGGHI--------KYVVA 175

  Fly   285 ARL-----AGAIIQKKIQKFLRSKLVLSFLALLLIIKIIKIKLFWLLPIVIGVGAAKKLLLKFLL 344
            |.|     ||.:..|.:.......||:|.:||                .:.|:.|.|||.
  Fly   176 ALLTAMGIAGPLGLKALAAIAGKALVISKVAL----------------TIAGIIALKKLF----- 219

  Fly   345 FLFPALSHLFKLCSHYQQSYHAPAKYHHHHHLIDHHHTVVPPWHSGEHH 393
                         ||                  ||........|:|||:
  Fly   220 -------------SH------------------DHSEETSFQVHAGEHN 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Osi17	NP_001262307.1	DUF1676	180..270	CDD:285181	23/106 (22%)
		Prefoldin	603..>680	CDD:298833
		DM4_12	661..745	CDD:299813
Osi21	NP_609501.1	DUF1676	79..>152	CDD:285181	21/89 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21879
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100