DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Osi12 and Osi17

DIOPT Version :9

Sequence 1:	NP_649631.1	Gene:	Osi12 / 40766	FlyBaseID:	FBgn0037419	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001262307.1	Gene:	Osi17 / 40774	FlyBaseID:	FBgn0037427	Length:	750	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	57/343 - (16%)
Similarity:	102/343 - (29%)	Gaps:	131/343 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 VPCLKKKAISFIDRLAPIDAINVAEGIKLVRLETAPRPPATSENELESSLPRSGSDRD--AKLTN 125
            |.|.:|...|::|.:..:..:||.:.:|..:.:...:.....|   |.|..|:.|...  .::|:
  Fly   169 VSCFQKNVFSYLDNVLDVQDVNVTQRLKFFKNQVDYQVDKEKE---EHSEARAASAETPIEEVTS 230

  Fly   126 MLIERLSYFFNGHSLQVSFPKL----TSDEIGRGLEEGRG------------------------K 162
            .|..:...|...|.|:|..|::    .:..|.....||.|                        |
  Fly   231 ALYGKSIKFAMTHDLEVDLPEVMFNGATFRISPRAIEGNGIIAKLELIPKQVVKARLAGAIIQKK 295

  Fly   163 MKKMMG-----------MMMMGMAMKMMGMIPIAMGALYILAGKALIISKIALLLAGIIGLKKLM 216
            ::|.:.           :::..:.:|:..::||.:|   :.|.|.|::..:..|...:..|.||.
  Fly   296 IQKFLRSKLVLSFLALLLIIKIIKIKLFWLLPIVIG---VGAAKKLLLKFLLFLFPALSHLFKLC 357

  Fly   217 SGKSSGGSS-------------------GWSSG-----------------------------GGG 233
            |.......:                   .|.||                             ..|
  Fly   358 SHYQQSYHAPAKYHHHHHLIDHHHTVVPPWHSGEHHSVPEIIYTHPPKGHPSAYLHGAPVHESYG 422

  Fly   234 GG-----GGWSSGGGGGGG------------------------------GGWDRRSLTEAQELAY 263
            .|     |.|.:.|.|.|.                              ..|...:..:||...:
  Fly   423 PGFEHFEGAWENSGPGLGSEYIGDINRVAQIEENAHFFKPHPANDAGVLHAWGLGTTQQAQHQTH 487

  Fly   264 RAHHQEQVAHAQSRPQLQ 281
            :.|.:..|.. |:||..|
  Fly   488 QPHQRWSVTQ-QARPPTQ 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Osi12	NP_649631.1	DUF1676	74..159	CDD:285181	17/90 (19%)
Osi17	NP_001262307.1	DUF1676	180..270	CDD:285181	19/92 (21%)
		Prefoldin	603..>680	CDD:298833
		DM4_12	661..745	CDD:299813
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21879
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100