Protein Alignment NPFR and prlh2r

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001108619.1
• Gene: prlh2r / 797157
• ZFINID: ZDB-GENE-120411-41
• Length: 371
• Species: Danio rerio
• Alignment Length: 331
• Identity: 97/331 - (29%)
• Similarity: 163/331 - (49%)
• Gaps: 25/331 - (7%)

  Fly    88 MLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEIL-SKY 151
            :.|.:|.:|::....||.|::|.:.....:.:..|..|.|||:.||::||..:|||..... .:.
Zfish    36 LFIPLYTMLVLIACSGNLLLLILIGLNKKLHSTTNFLIGNLALVDLVMCLFCVPLTAFYAFDERG 100

  Fly   152 WPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYP--TRDSLQFVGAVTILAGIWALA 214
            |.:|  ..:|..:.::|...:|.:.:|:||||.|||.|:.||  .|....|.|  .::..||..|
Zfish   101 WVFG--QFMCHFVTLMQTATVFAAVLSLTAIAVDRYVVVAYPIRRRGGRWFCG--WLVVSIWLCA 161

  Fly   215 LLLASPLFVYKELINTDTPALLQQIGLQDTIPYCIEDWPSRN-GRFYYSIFSLCVQYLVPILIVS 278
            |.:::|..::...::      |.:.|.:..:  |.|.|..:. .|..||.|.|.:.|.||:..||
Zfish   162 LAMSTPTALHTVYLD------LSETGHEMAV--CEEFWHGQELSRLIYSCFFLLLSYFVPLAAVS 218

  Fly   279 VAYFGIYNKLKSRITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADME 343
            ::|..|...|:.|.| ..:.|::...:.:.||:.::|..||:...:.|..|||||...||..|::
Zfish   219 ISYCAISCHLQHRAT-PRLMAATPSNQEKWGRKRRKTFRLLLVSVLSFAFSWLPLQIVNLIRDLD 282

  Fly   344 RSPVTQS---MLVRYAICHMIGMSSACSNPLLYGWLNDNF-----RKEFQELLCRCSDTNVALNG 400
            ......|   :.|....||::.|||||.||.:|..|:..|     ...||:....|:.:::..:.
Zfish   283 TDFAILSKNHVNVIQVSCHLLAMSSACYNPFIYASLHKKFLSYLCHNMFQKRKAHCTQSSITTSS 347

  Fly   401 HTTGCN 406
            ..|..|
Zfish   348 RMTRLN 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	92/307 (30%)
		TM helix 1	88..114	CDD:320331	7/25 (28%)
		TM helix 2	121..146	CDD:320331	12/24 (50%)
		TM helix 3	161..191	CDD:320331	12/29 (41%)
		TM helix 4	202..223	CDD:320331	6/20 (30%)
		TM helix 5	258..287	CDD:320331	12/28 (43%)
		TM helix 6	310..340	CDD:320331	12/29 (41%)
		TM helix 7	352..377	CDD:320331	11/24 (46%)
prlh2r	NP_001108619.1	7tmA_PrRP_R	35..326	CDD:320516	92/302 (30%)
		TM helix 1	36..62	CDD:320516	7/25 (28%)
		TM helix 2	69..94	CDD:320516	12/24 (50%)
		TM helix 3	108..138	CDD:320516	12/29 (41%)
		TM helix 4	149..170	CDD:320516	7/22 (32%)
		TM helix 5	198..227	CDD:320516	12/28 (43%)
		TM helix 6	249..279	CDD:320516	12/29 (41%)
		TM helix 7	294..319	CDD:320516	11/24 (46%)