DRSC/TRiP Functional Genomics Resources

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Protein Alignment NPFR and qrfpr

DIOPT Version :9

Sequence 1:NP_001246947.1 Gene:NPFR / 40754 FlyBaseID:FBgn0037408 Length:489 Species:Drosophila melanogaster
Sequence 2:XP_012820557.1 Gene:qrfpr / 779748 XenbaseID:XB-GENE-994316 Length:456 Species:Xenopus tropicalis


Alignment Length:325 Identity:91/325 - (28%)
Similarity:163/325 - (50%) Gaps:56/325 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 VLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSI 159
            ::.|....||:||:..|.|...|||..|:||.:||:||||:....:|.|:::.:|..|..|  :.
 Frog    88 LIFVLALFGNSLVLYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPFTMLQNISSNWLGG--AF 150

  Fly   160 LCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVG--AVTILAGIWALALLLASPL- 221
            .||.:..:|:..|....:::|.||.:|:|.||:|.:...|:..  |.|:|..:|.:|.::..|: 
 Frog   151 ACKMVPFVQSTAIVTEILTMTCIAVERHQGIVHPLKMKWQYTNRRAFTMLGIVWLIAAVVGIPMW 215

  Fly   222 ----------FVYKELINTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILI 276
                      |:|::          |.:       .|:|.|.|:..:..|:.|.|.:.:|:|:.:
 Frog   216 HAQRLEVKYDFLYEK----------QYV-------CCLEAWNSQVHQKIYTTFILVILFLLPLTV 263

  Fly   277 VSVAYFGIYNKL--KSRI---TVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPL--- 333
            :.:.|..|..:|  |.|:   :|:.....|...|:  .|:.||...::|::.::|.|.|.|.   
 Frog   264 MLLLYSKIGYELWIKKRVGDASVLQTIHGSEMSKI--ARKKKRAIIMMITVVVLFAVCWAPFHVV 326

  Fly   334 -------NFFNLYADMERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQELLCRC 391
                   ||.|.|.|:       ::.:.:||..:||..::..||::|.::|:||:|.|...||.|
 Frog   327 HMMIEYSNFENEYDDV-------TIKIIFAIVQIIGFFNSICNPIVYAFMNENFKKNFLSALCFC 384

  Fly   392  391
             Frog   385  384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NPFRNP_001246947.1 7tm_4 98..>195 CDD:304433 36/96 (38%)
7tm_1 103..373 CDD:278431 81/297 (27%)
qrfprXP_012820557.1 7tmA_QRFPR 80..377 CDD:320333 87/316 (28%)
TM helix 1 81..107 CDD:320333 6/18 (33%)
TM helix 2 114..140 CDD:320333 11/25 (44%)
TM helix 3 152..182 CDD:320333 9/29 (31%)
TM helix 4 195..216 CDD:320333 6/20 (30%)
TM helix 5 245..270 CDD:320333 6/24 (25%)
TM helix 6 300..330 CDD:320333 8/29 (28%)
TM helix 7 345..370 CDD:320333 7/24 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3897
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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