DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NPFR and Npy2r

DIOPT Version :9

Sequence 1:	NP_001246947.1	Gene:	NPFR / 40754	FlyBaseID:	FBgn0037408	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_076458.1	Gene:	Npy2r / 66024	RGDID:	620475	Length:	381	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	124/396 - (31%)
Similarity:	196/396 - (49%)	Gaps:	61/396 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 SDLNET--------GSRPL----------DPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALG 103
            :|.|:|        ||.|.          :|.|||   |.:.|:.  ..:||..|..:|:.|.:|
  Rat     8 ADENQTVEVKVELYGSGPTTPRGELPPDPEPELID---STKLVEV--QVVLILAYCSIILLGVVG 67

  Fly   104 NTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQ 168
            |:||:..||:...|||..|.||.|||::|||:..:.:|.||...|...|..|  .:||..:...|
  Rat    68 NSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMG--PVLCHLVPYAQ 130

  Fly   169 ALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTP 233
            .|.:.||||::|.||.||::.|||.....:....:..|:...|.::.||||||.:::|
  Rat   131 GLAVQVSTITLTVIALDRHRCIVYHLESKISKQISFLIIGLAWGVSALLASPLAIFRE------- 188

  Fly   234 ALLQQIGLQDTIP-----YCIEDWPSRNGRFY---YSIFSLCVQYLVPILIVSVAYFGIYNKLKS 290
                 ..|.:.||     .|.|.||......|   ||:.:|.:.|::|:.|:|.:|..|::|||:
  Rat   189 -----YSLIEIIPDFEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKLKN 248

  Fly   291 RITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADMERS--PVTQSMLV 353
            .::..|......||:       .:|..:|:.:.::|.||||||:.|.|..|::..  .:.:..|:
  Rat   249 HVSPGAASDHYHQRR-------HKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSHVLDLKEYKLI 306

  Fly   354 RYAICHMIGMSSACSNPLLYGWLNDNFRKEFQELLCRCSDTNVALNGHTTGCNVQAAARRRRKLG 418
             :.:.|:|.|.|..:|||||||:|.|:||.|.... ||.....|::.     .|....:.::.|.
  Rat   307 -FTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAF-RCEQRLDAIHS-----EVSMTFKAKKNLE 364

  Fly   419 AELSKG 424
            .:.:.|
  Rat   365 VKKNNG 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tm_4	98..>195	CDD:304433	41/96 (43%)
NPFR	NP_001246947.1	7tm_1	103..373	CDD:278431	92/279 (33%)
Npy2r	NP_076458.1	7tm_4	61..340	CDD:304433	103/300 (34%)
Npy2r	NP_076458.1	7tm_1	67..325	CDD:278431	92/279 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010