Protein Alignment NPFR and prlhr2a

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001034615.1
• Gene: prlhr2a / 654782
• ZFINID: ZDB-GENE-060209-1
• Length: 370
• Species: Danio rerio
• Alignment Length: 375
• Identity: 105/375 - (28%)
• Similarity: 184/375 - (49%)
• Gaps: 50/375 - (13%)

  Fly    50 NTTAINTS-------DLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLV 107
            |.|..|:|       .|..|.|...:|    :|:....:.| :..::|..|.::::.|..||.|:
Zfish    20 NVTMENSSVGRIYEVMLQSTNSTKRNP----QFVGVELLQS-FKPLIIPCYALVVLVGVFGNYLL 79

  Fly   108 VIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILS-KYWPYGSCSILCKTIAMLQALC 171
            :..:.:...|....|.||.|||.||:|:|...:|.||....: :.|.:|  ..:|..:.::|.:.
Zfish    80 LYVICQTKKMHNVTNFFIGNLAFSDMLMCATCVPFTLAYAFNPRGWVFG--RFMCYLVFLIQPVT 142

  Fly   172 IFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTPALL 236
            ::||..::|||..|||...|:|.:..:..:....:|:|||.|:..|.:|...:           .
Zfish   143 VYVSVFTLTAIGVDRYYATVHPLKKRISVLACTYLLSGIWILSCGLVAPAVAH-----------T 196

  Fly   237 QQIGLQD---TIPYCIEDWPSR-NGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVAV 297
            ..:..:|   ||  |.|.|..: ..|..|:..:|.:.|::|:..:.::|..|..||::  .||..
Zfish   197 YHVEFKDEGFTI--CEEFWMGQEKERLAYAYSTLFITYVLPLSALCISYLCISVKLRN--CVVPG 257

  Fly   298 QASSAQRKVERGRRMKRTNCLLISIAI-IFGVSWLPLNFFNLYADMERSPVTQS-MLVRYAICHM 360
            ..:.:|.:.:|.|  ||....|:|:.: .||:.|||::.||:..|::...:.:. .|:...:||:
Zfish   258 HRTQSQAEAQRAR--KRKTFRLVSLVVAAFGICWLPISVFNVLRDIDIDLIDKRYFLLIQLLCHL 320

  Fly   361 IGMSSACSNPLLYGWLNDNFRKEFQELL-C-----------RCSDTNVAL 398
            .||||:|.||.||.||:|.||.|.:::. |           .|:..:|.|
Zfish   321 CGMSSSCCNPFLYAWLHDRFRAELRKMFTCHRRIGIGIPANNCATASVVL 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	90/302 (30%)
		TM helix 1	88..114	CDD:320331	6/25 (24%)
		TM helix 2	121..146	CDD:320331	13/24 (54%)
		TM helix 3	161..191	CDD:320331	10/29 (34%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	7/28 (25%)
		TM helix 6	310..340	CDD:320331	12/30 (40%)
		TM helix 7	352..377	CDD:320331	13/24 (54%)
prlhr2a	NP_001034615.1	7tmA_PrRP_R	59..344	CDD:320516	90/303 (30%)
		TM helix 1	60..86	CDD:320516	6/25 (24%)
		TM helix 2	93..118	CDD:320516	13/24 (54%)
		TM helix 3	132..162	CDD:320516	10/29 (34%)
		TM helix 4	173..194	CDD:320516	7/20 (35%)
		TM helix 5	220..249	CDD:320516	7/28 (25%)
		TM helix 6	269..299	CDD:320516	12/31 (39%)
		TM helix 7	312..337	CDD:320516	13/24 (54%)