Protein Alignment NPFR and Npffr1

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_006256547.1
• Gene: Npffr1 / 64107
• RGDID: 621570
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 126/419 - (30%)
• Similarity: 193/419 - (46%)
• Gaps: 39/419 - (9%)

  Fly    55 NTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRT 119
            |.||:..:.:..|      .|.|.....||...|.|:.|.::.:...:|||||...|::...|||
  Rat    54 NGSDVETSIATSL------TFSSYYQHSSPVAAMFIAAYVLIFLLCMVGNTLVCFIVLKNRHMRT 112

  Fly   120 ARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAF 184
            ..|:||||||:||||:.:..||.||::.|...||:.:.:  ||...::|.:.:..|..::.|||.
  Rat   113 VTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNAT--CKMSGLVQGMSVSASVFTLVAIAV 175

  Fly   185 DRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTPALLQQIGLQDTIPYCI 249
            :|::.||:|.|:.|....|:..:|.|||||||:..|..|...:...:...:|........:..|.
  Rat   176 ERFRCIVHPFREKLTLRKALFTIAVIWALALLIMCPSAVTLTVTREEHHFMLDARNRSYPLYSCW 240

  Fly   250 EDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVAVQASSAQRKVER------ 308
            |.||.:..|..|:.......||||:.::.|.|..|..||        .||....|..|.
  Rat   241 EAWPEKGMRKVYTAVLFAHIYLVPLALIVVMYVRIARKL--------CQAPGPARDTEEAVAEGG 297

  Fly   309 --GRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADM-ERSPVTQSMLVRYA--ICHMIGMSSACS 368
              .||..|...:|:.:|:.|.:|||||....|..|. |.|.:...:|..||  :.|.:....:.:
  Rat   298 RTSRRRARVVHMLVMVALFFTLSWLPLWVLLLLIDYGELSELQLHLLSVYAFPLAHWLAFFHSSA 362

  Fly   369 NPLLYGWLNDNFRKEFQELLCRCSDTNVALNGHTTGCNVQAAARR-----RRKLGAELSKGELKL 428
            ||::||:.|:|||:.||...      ...|.......:.||.:.|     ||::..::...:..|
  Rat   363 NPIIYGYFNENFRRGFQAAF------RAQLCWPPWAAHKQAYSERPNRLLRRRVVVDVQPSDSGL 421

  Fly   429 LGPGGAQSGTAGGEGGLAATDFMTGHHEG 457
            ....|..||.. |.|.|...:....|.:|
  Rat   422 PSESGPSSGVP-GPGRLPLRNGRVAHQDG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	101/306 (33%)
		TM helix 1	88..114	CDD:320331	9/25 (36%)
		TM helix 2	121..146	CDD:320331	15/24 (63%)
		TM helix 3	161..191	CDD:320331	8/29 (28%)
		TM helix 4	202..223	CDD:320331	10/20 (50%)
		TM helix 5	258..287	CDD:320331	9/28 (32%)
		TM helix 6	310..340	CDD:320331	12/29 (41%)
		TM helix 7	352..377	CDD:320331	8/26 (31%)
Npffr1	XP_006256547.1	7tmA_NPFFR1	80..378	CDD:320647	101/307 (33%)
		TM helix 1	81..107	CDD:320647	9/25 (36%)
		TM helix 2	114..140	CDD:320647	15/25 (60%)
		TM helix 3	152..182	CDD:320647	8/29 (28%)
		TM helix 4	193..214	CDD:320647	10/20 (50%)
		TM helix 5	249..278	CDD:320647	9/28 (32%)
		TM helix 6	301..331	CDD:320647	12/29 (41%)
		TM helix 7	346..371	CDD:320647	7/24 (29%)