Protein Alignment NPFR and npffr2a

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001098579.1
• Gene: npffr2a / 560955
• ZFINID: ZDB-GENE-060526-183
• Length: 422
• Species: Danio rerio
• Alignment Length: 382
• Identity: 109/382 - (28%)
• Similarity: 184/382 - (48%)
• Gaps: 38/382 - (9%)

  Fly    49 LNTTAINTSDLNET---GSR----PLDPV-LIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNT 105
            ||.|.::  |.|.|   ||.    ||:.: .:..:|...:|.:    :.|..|.::.:...:||.
Zfish     7 LNITLVD--DGNWTFINGSSEFFLPLNNITYVGYYLHQPSVAA----VFIVSYLLIFLVCMIGNG 65

  Fly   106 LVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQAL 170
            :|...|:|...|||..|||||||||||||:.:..||.||::.:...||:|  |::||...|:|.:
Zfish    66 VVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLLDNIITGWPFG--SMVCKMSGMVQGI 128

  Fly   171 CIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTPAL 235
            .:..|..::.|||.||::.||||.:..|....|..|:..||.||:.:..|..|..::.......:
Zfish   129 SVSASVFTLVAIAVDRFRCIVYPFKQKLTISTATFIIVIIWVLAVSIMCPSGVMLQVTKEQNIRV 193

  Fly   236 LQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITV----VA 296
            .:.........:|.|:||::..|..|:.......||.|:.::.:.|        :||.:    .|
Zfish   194 FRGNNRSSPFYWCRENWPNQEMRKIYTTVLFANIYLAPLSLIVIMY--------ARIGITLFKTA 250

  Fly   297 VQASSAQRKVER---GRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADMERSPVTQSMLVR---Y 355
            :.|........|   .::.:|...:|:.:|::|.:|||||....:..|..:....|..::.   |
Zfish   251 MPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSWLPLWTLMMLTDYVKLTEHQYRVINIYIY 315

  Fly   356 AICHMIGMSSACSNPLLYGWLNDNFRKEFQEL----LCRCSDTNVALNGHTTGCNVQ 408
            ...|.:...::..||::||:.|:|||:.||.:    ||.....:...:....|.:||
Zfish   316 PFAHWLAFFNSSVNPIIYGFFNENFRRGFQAIFKFGLCPVGGQHRTYSHRVQGNSVQ 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	90/305 (30%)
		TM helix 1	88..114	CDD:320331	6/25 (24%)
		TM helix 2	121..146	CDD:320331	17/24 (71%)
		TM helix 3	161..191	CDD:320331	10/29 (34%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	6/28 (21%)
		TM helix 6	310..340	CDD:320331	9/29 (31%)
		TM helix 7	352..377	CDD:320331	6/27 (22%)
npffr2a	NP_001098579.1	7tmA_NPFFR2	47..344	CDD:320646	90/310 (29%)
		TM helix 1	48..74	CDD:320646	6/25 (24%)
		TM helix 2	81..107	CDD:320646	17/25 (68%)
		TM helix 3	119..149	CDD:320646	10/29 (34%)
		TM helix 4	160..181	CDD:320646	7/20 (35%)
		TM helix 5	216..245	CDD:320646	8/36 (22%)
		TM helix 6	267..297	CDD:320646	9/29 (31%)
		TM helix 7	312..337	CDD:320646	6/24 (25%)