Protein Alignment NPFR and NPY5R

DIOPT Version :9

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_011530317.1
• Gene: NPY5R / 4889
• HGNCID: 7958
• Length: 452
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 111/444 - (25%)
• Similarity: 187/444 - (42%)
• Gaps: 126/444 - (28%)

  Fly    50 NTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRK 114
            ||.|...||.         ||..|   ...:||...| .||.:|..:.:.|.:||.|:::|:::|
Human    25 NTAATRNSDF---------PVWDD---YKSSVDDLQY-FLIGLYTFVSLLGFMGNLLILMALMKK 76

  Fly   115 PIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTISI 179
            ...:|..|..|.|||.||:|:.|...|.||..:|...|.:|  .::|..:..||.:.:.|||:.:
Human    77 RNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFG--KVMCHIMPFLQCVSVLVSTLIL 139

  Fly   180 TAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELI---NTDTPALLQQIGL 241
            .:||..||.:|.:|..::|.......::|.:|.|...:.|||.|:..|:   .|...|||....|
Human   140 ISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYL 204

  Fly   242 QDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGI-----------YNKLKS----R 291
                  |:|.|||.:.|..::|..|.|||::|::.::|::..:           .|:|:.    .
Human   205 ------CVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMIN 263

  Fly   292 ITVVAVQASSAQRKV-------------ERGRRMKRTNCLLIS---------------------- 321
            :|:...:.|..|.|:             .|.|..|:|.|:|.:
Human   264 LTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRS 328

  Fly   322 ---------------------------------------------------IAIIFGVSWLPLNF 335
                                                               :.::|.|||:||:.
Human   329 QLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHL 393

  Fly   336 FNLYADMERSPVT-QSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQELL 388
            |::..|...:.:: :...:.|.|||::||.|.|.||:|||:||:..:.:...|:
Human   394 FHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tm_4	98..>195	CDD:304433	34/96 (35%)
		7tm_1	103..373	CDD:278431	90/374 (24%)
NPY5R	XP_011530317.1	7tm_4	56..>178	CDD:304433	38/123 (31%)
		7tm_1	65..432	CDD:278431	90/374 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4091
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H21241
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D275052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020