Protein Alignment NPFR and Gpr165

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001100052.1
• Gene: Gpr165 / 296866
• RGDID: 1564566
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 337
• Identity: 87/337 - (25%)
• Similarity: 173/337 - (51%)
• Gaps: 27/337 - (8%)

  Fly    55 NTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRT 119
            ||.||.:| |.|||..::.:       |......|:..|.:::....:||.::...:::...:.|
  Rat    79 NTGDLADT-SGPLDLEIVSQ-------DEQVQFWLVVGYTIVVFAAIIGNWVLNHIIMKYKRVHT 135

  Fly   120 ARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAF 184
            |..||::|:::::::|.|::.|.|::..|.....:|  .:.|......|..|.:|:.:|:.||:.
  Rat   136 ATGLFVVNISVTNMMLALLSSPFTMVRYLCNSLVFG--KMTCHLSRFAQYSCAYVTVMSMAAISL 198

  Fly   185 DRYQVIVYPTRDSL-QFVGAVTILAGIWALALLLASPLFVYKELINTDTPALLQQIGLQDTIPYC 248
            ||::|::||.:..: ...|.|.|:. ||.::...|.|..||::|...:.....::.....:.||
  Rat   199 DRHRVMLYPLKARITPMQGNVCIII-IWIVSTCAALPHAVYQKLYQVEFGNTTEESACLPSFPY- 261

  Fly   249 IEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKL--KSRITVVAVQASSAQRKVERGRR 311
                .|::...|..:.:..:.:::|:|::...|..:..||  ...:..:.:.....|    ||::
  Rat   262 ----TSKSTWKYLDLGTFLLFFILPLLVLVAVYGHVAKKLWIHDAVDDINIHTYICQ----RGKK 318

  Fly   312 MKRTNCLLISIAIIFGVSWLPLNFFNLYADMERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWL 376
             |:|..:|:::.:::.:|||||   |||..:..|....|....|...|.:.:||:|.||.:|.||
  Rat   319 -KQTLKMLMTVVLLYTISWLPL---NLYLVLLSSESISSHNGLYFFLHWLAISSSCYNPYIYCWL 379

  Fly   377 NDNFRKEFQELL 388
            :|:||.|.|:::
  Rat   380 SDSFRIEVQKVI 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	75/298 (25%)
		TM helix 1	88..114	CDD:320331	4/25 (16%)
		TM helix 2	121..146	CDD:320331	7/24 (29%)
		TM helix 3	161..191	CDD:320331	10/29 (34%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	4/28 (14%)
		TM helix 6	310..340	CDD:320331	10/29 (34%)
		TM helix 7	352..377	CDD:320331	9/24 (38%)
Gpr165	NP_001100052.1	7tmA_GPR83	103..387	CDD:320511	75/299 (25%)
		TM helix 1	104..130	CDD:320511	4/25 (16%)
		TM helix 2	137..162	CDD:320511	7/24 (29%)
		TM helix 3	175..205	CDD:320511	10/29 (34%)
		TM helix 4	216..237	CDD:320511	7/21 (33%)
		TM helix 5	267..296	CDD:320511	4/28 (14%)
		TM helix 6	316..346	CDD:320511	12/33 (36%)
		TM helix 7	355..380	CDD:320511	9/24 (38%)