Protein Alignment NPFR and Npy5r

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_037001.1
• Gene: Npy5r / 25340
• RGDID: 3199
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 413
• Identity: 103/413 - (24%)
• Similarity: 178/413 - (43%)
• Gaps: 113/413 - (27%)

  Fly    80 AVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTL 144
            :||...| .||.:|..:.:.|.:||.|:::||::|...:|..|..|.|||.||:|:.|...|.||
  Rat    36 SVDDLQY-FLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL 99

  Fly   145 MEILSKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAG 209
            ..:|...|.:|..  :|..:..||.:.:.|||:.:.:||..||.:|.:|..::|.......::|.
  Rat   100 TSVLLDQWMFGKA--MCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIAT 162

  Fly   210 IWALALLLASPLFVYKELI---NTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYL 271
            :|.|...:.|||.|:..|:   .|...|||....|      |:|.|||.:.|..::|..|.|||:
  Rat   163 VWTLGFAICSPLPVFHSLVELKETFGSALLSSKYL------CVESWPSDSYRIAFTISLLLVQYI 221

  Fly   272 VPILIVSVAYFGI-----------YNKLKSRITV-VAVQASSAQR----------------KVER 308
            :|::.::|::..:           .|:|:....: :.:|.|...|                :..|
  Rat   222 LPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHR 286

  Fly   309 GRRMKRTNCLLIS---------------------------------------------------- 321
            .|..|:|.|:|.:
  Rat   287 RRYSKKTACVLPAPAGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRV 351

  Fly   322 --------------------IAIIFGVSWLPLNFFNLYADMERSPVT-QSMLVRYAICHMIGMSS 365
                                :.::|.|||:||:.|::..|...:.:: :...:.|.|||::||.|
  Rat   352 KRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMS 416

  Fly   366 ACSNPLLYGWLNDNFRKEFQELL 388
            .|.||:|||:||:..:.:.:.|:
  Rat   417 CCLNPILYGFLNNGIKADLRALI 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	99/399 (25%)
		TM helix 1	88..114	CDD:320331	9/25 (36%)
		TM helix 2	121..146	CDD:320331	12/24 (50%)
		TM helix 3	161..191	CDD:320331	10/29 (34%)
		TM helix 4	202..223	CDD:320331	6/20 (30%)
		TM helix 5	258..287	CDD:320331	8/39 (21%)
		TM helix 6	310..340	CDD:320331	12/101 (12%)
		TM helix 7	352..377	CDD:320331	13/24 (54%)
Npy5r	NP_037001.1	7tmA_NPY5R	42..435	CDD:320520	100/401 (25%)
		TM helix 1	43..69	CDD:320520	9/25 (36%)
		TM helix 2	76..101	CDD:320520	12/24 (50%)
		TM helix 3	114..144	CDD:320520	10/29 (34%)
		TM helix 4	155..176	CDD:320520	6/20 (30%)
		TM helix 5	208..237	CDD:320520	8/28 (29%)
		TM helix 6	360..390	CDD:320520	7/29 (24%)
		TM helix 7	403..428	CDD:320520	13/24 (54%)