Protein Alignment NPFR and npr-13

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_506659.2
• Gene: npr-13 / 191160
• WormBaseID: WBGene00013883
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 362
• Identity: 101/362 - (27%)
• Similarity: 177/362 - (48%)
• Gaps: 60/362 - (16%)

  Fly    92 MYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGS 156
            :|.::::.|.:||.|::.:::.:..:..| |:|::|||:||||||:..:|:|.:....|.|.:|
 Worm    35 LYFLILIIGLVGNGLLITSILMRKKLSVA-NIFLINLAVSDLLLCITAVPITPVLAFMKRWIFG- 97

  Fly   157 CSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPL 221
             .|:||.:...||..:.:|:.|:..||.|||:.||.|.|:......|..:|...|.:|.|.:.||
 Worm    98 -IIMCKLVPTCQAFSVLISSWSLCYIAIDRYRSIVTPLREPWSDRHARWLLMFTWVVAFLASYPL 161

  Fly   222 FVYKELINTDTPALLQQIGLQDTIPYCIE-DWPSRN-GRFYYSIFSLCVQYLVPILIVSVAYFGI 284
            : |.:.:.|   .:::.:.|..  .:|.| :|.|.. .:..|:...|.:|.::|.:|:|..|..|
 Worm   162 Y-YSQNLKT---MVIENVTLCG--DFCGEFNWQSDEISKLTYTTSLLIIQLIIPAIIMSFCYLMI 220

  Fly   285 YNKLKS-------RITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADM 342
            ..|:::       .:...|.||.:|.||       :|...:||.:.|:|...|.||:..||:.|:
 Worm   221 LQKVQTDWLVDEGSMLTAAQQAQTAVRK-------RRVMYVLILMVIVFMACWFPLSAVNLFRDL 278

  Fly   343 ERSPVTQSMLVRYAIC-------------------HMIGMSSACSNPLLYGWLNDNFRKEFQELL 388
            .         :|:..|                   |:|.|:|...||:||.|::...|:..::.:
 Worm   279 G---------MRFEFCQTVYKVLMMDQMYFKLLNVHVIAMTSIVWNPVLYFWMSKRHRRALKDDM 334

  Fly   389 CRCSD----TNV-ALNGHTTGCNVQAAARR--RRKLG 418
            ...::    ||| .|:..|...:|....||  .|.||
 Worm   335 TWLTNARRHTNVGVLSRFTPSPSVSVVYRRTLERHLG 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	90/319 (28%)
		TM helix 1	88..114	CDD:320331	5/21 (24%)
		TM helix 2	121..146	CDD:320331	13/24 (54%)
		TM helix 3	161..191	CDD:320331	11/29 (38%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	8/28 (29%)
		TM helix 6	310..340	CDD:320331	10/29 (34%)
		TM helix 7	352..377	CDD:320331	11/43 (26%)
npr-13	NP_506659.2	7tmA_NPYR-like	32..330	CDD:320331	90/319 (28%)
		TM helix 1	32..57	CDD:320331	5/21 (24%)
		TM helix 2	63..88	CDD:320331	14/25 (56%)
		TM helix 3	101..131	CDD:320331	11/29 (38%)
		TM helix 4	142..163	CDD:320331	7/21 (33%)
		TM helix 5	194..223	CDD:320331	8/28 (29%)
		TM helix 6	246..276	CDD:320331	12/36 (33%)
		TM helix 7	298..323	CDD:320331	9/24 (38%)