Protein Alignment NPFR and Npy4r

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_032945.3
• Gene: Npy4r / 19065
• MGIID: 105374
• Length: 375
• Species: Mus musculus
• Alignment Length: 126
• Identity: 26/126 - (20%)
• Similarity: 50/126 - (39%)
• Gaps: 30/126 - (23%)

  Fly   159 TNCTTKTRGVNAGWGAIRIGVYHK---------HMKRWLDHFPI-----ENIHIVDGEKLISNPA 209
            ||..|.|:|::        |:|.:         ...:|.....|     .|:.|::...:::..|
Mouse   119 TNGETTTQGLD--------GLYERCAQYKKDGADFAKWRCVLKITPTTPSNLAIIENANVLARYA 175

  Fly   210 DEISATEKFLGLKPVAKPEKF--GVDPIKKFPCIKNEDGKLHCLGKTKGRHHPDVEPSVLK 268
                :..:..|:.|:.:||..  |...:|:  |....:..|..:.|....||..:|.::||
Mouse   176 ----SICQMHGIVPIVEPEILPDGDHDLKR--CQYVTEKVLAAVYKALSDHHVYLEGTLLK 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	26/126 (21%)
		TM helix 1	88..114	CDD:320331
		TM helix 2	121..146	CDD:320331
		TM helix 3	161..191	CDD:320331	6/38 (16%)
		TM helix 4	202..223	CDD:320331	2/20 (10%)
		TM helix 5	258..287	CDD:320331	5/11 (45%)
		TM helix 6	310..340	CDD:320331
		TM helix 7	352..377	CDD:320331
Npy4r	NP_032945.3	7tmA_NPY4R	43..333	CDD:320519	26/126 (21%)
		TM helix 1	43..69	CDD:320519
		TM helix 2	76..101	CDD:320519
		TM helix 3	114..144	CDD:320519	7/32 (22%)
		TM helix 4	155..176	CDD:320519	3/24 (13%)
		TM helix 5	211..240	CDD:320519	6/20 (30%)
		TM helix 6	258..288	CDD:320519
		TM helix 7	301..326	CDD:320519