Protein Alignment NPFR and npr-22

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001023541.1
• Gene: npr-22 / 190424
• WormBaseID: WBGene00022004
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 92/324 - (28%)
• Similarity: 159/324 - (49%)
• Gaps: 44/324 - (13%)

  Fly    86 YHMLISM-------YGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLT 143
            ||:..||       |.:|.|....||.||::.::....:|||.|:.|||||::|||:.:..:|.:
 Worm    43 YHLTPSMKMLCILFYSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVADLLISVFCIPFS 107

  Fly   144 LMEIL---SKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFV--GA 203
            ..::|   .:.|.:|  |::|..:|.|||:.:|:|..::..|:|||:..|::....:::..  .|
 Worm   108 YWQVLIYDDQRWLFG--SMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRRA 170

  Fly   204 VTILAGIWALALLLASPLFVYKELINTDTPALLQQIGLQDTIPYCIEDW-----PSRNGRFYYSI 263
            :.::|..|..::|:|.||.........           ||.:|.|.|:|     .....|..||.
 Worm   171 LYLVAATWIFSILMALPLLFTTRFFED-----------QDGLPNCGENWTYFGDSGEQVRKVYSS 224

  Fly   264 FSLCVQYLVP--ILIVSVAYFGIYNKLKSRITVVAVQASSAQRK-VERGRRMKRTNCLLISIAII 325
            ..|.:||:||  :||::..:.|| ....||  |..:|..:.::. |:|...:|:...::|.|:.:
 Worm   225 MVLILQYVVPQAVLIITYTHIGI-KMWNSR--VPGMQNGATKKMIVDRHESVKKLVPMVILISAL 286

  Fly   326 FGVSWLPLNFF-----NLYADMERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEF 384
            |.:.||||...     ..|.|:..   ...:|..:...|.:.||.:..||::|...|..||:.|
 Worm   287 FALCWLPLLILINVIPEFYPDINS---WGYILYLWWFAHGLAMSHSMVNPIIYFIRNARFREGF 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	89/320 (28%)
		TM helix 1	88..114	CDD:320331	9/32 (28%)
		TM helix 2	121..146	CDD:320331	10/24 (42%)
		TM helix 3	161..191	CDD:320331	11/29 (38%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	12/30 (40%)
		TM helix 6	310..340	CDD:320331	8/34 (24%)
		TM helix 7	352..377	CDD:320331	7/24 (29%)
npr-22	NP_001023541.1	7tmA_PR4-like	51..347	CDD:320514	87/314 (28%)
		TM helix 1	52..78	CDD:320514	7/25 (28%)
		TM helix 2	85..110	CDD:320514	10/24 (42%)
		TM helix 3	126..156	CDD:320514	11/29 (38%)
		TM helix 4	169..190	CDD:320514	7/20 (35%)
		TM helix 5	219..248	CDD:320514	12/29 (41%)
		TM helix 6	271..301	CDD:320514	8/29 (28%)
		TM helix 7	315..340	CDD:320514	7/24 (29%)