DRSC/TRiP Functional Genomics Resources

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Protein Alignment NPFR and npr-5

DIOPT Version :9

Sequence 1:NP_001246947.1 Gene:NPFR / 40754 FlyBaseID:FBgn0037408 Length:489 Species:Drosophila melanogaster
Sequence 2:NP_001024265.1 Gene:npr-5 / 190386 WormBaseID:WBGene00021983 Length:433 Species:Caenorhabditis elegans


Alignment Length:352 Identity:100/352 - (28%)
Similarity:174/352 - (49%) Gaps:38/352 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 TVHALNTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVVI 109
            |.|:.|.:.|..::  ...::.:|.:.:|.::.:         :...:||.|.|.|..||..|:.
 Worm    25 TSHSNNGSCIQIAE--AIAAQGIDDITVDFYIRS---------IFTFLYGFLFVLGIFGNGGVLW 78

  Fly   110 AVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFV 174
            ||.|...:::|||:|:|||..:||:|....:|:|....::|.|.:|  |::|..:.:..:..:||
 Worm    79 AVARNKRLQSARNVFLLNLIFTDLILVFTAIPVTPWYAMTKDWAFG--SVMCHLVPLSNSCSVFV 141

  Fly   175 STISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTPALLQQI 239
            ::.|:|||:.|::..|..||:..:....|:.|...||.::.|:..|..:..|  :.|....:|  
 Worm   142 TSWSLTAISLDKFLHINDPTKQPVSIRQALAITFLIWIVSTLINLPYLMSFE--HVDGSFYVQ-- 202

  Fly   240 GLQDTIPYC-----IEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVAVQA 299
              ....|||     ..:|.|.|.|..|....:.:|::||:.:::..||.|..|:...:.:...|.
 Worm   203 --PGETPYCGHFCDEANWQSENSRKIYGTTVMLLQFVVPMAVITYCYFKILQKVSKDMIIQNAQF 265

  Fly   300 SSAQRKVERG---RRMKRTNCLLISIAIIFGVSWLPLNFFNLYADMERSPVTQSMLVR----YAI 357
            ..:..:.:|.   .|.|:.|.:||::.:.|...||||...||..|.::.|   ..|.|    :||
 Worm   266 CQSLTQKQRSDATSRKKKVNYILIAMVVTFIGCWLPLTLLNLVKDFKKEP---EWLKRQPFFWAI 327

  Fly   358 -CHMIGMSSACSNPLLYGWLNDNFRKE 383
             .|:|.||....||||:.||.   ||:
 Worm   328 NAHVIAMSLVVWNPLLFFWLT---RKQ 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NPFRNP_001246947.1 7tm_4 98..>195 CDD:304433 34/96 (35%)
7tm_1 103..373 CDD:278431 84/282 (30%)
npr-5NP_001024265.1 7tmA_NPYR-like 56..347 CDD:320331 90/310 (29%)
TM helix 1 58..82 CDD:320331 10/23 (43%)
TM helix 2 91..113 CDD:320331 9/21 (43%)
TM helix 3 129..151 CDD:320331 6/21 (29%)
TM helix 4 172..188 CDD:320331 4/15 (27%)
TM helix 5 225..248 CDD:320331 4/22 (18%)
TM helix 6 282..307 CDD:320331 9/24 (38%)
TM helix 7 323..347 CDD:320331 10/23 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3897
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.940

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