Protein Alignment NPFR and npr-14

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001379223.1
• Gene: npr-14 / 189211
• WormBaseID: WBGene00012275
• Length: 425
• Species: Caenorhabditis elegans
• Alignment Length: 379
• Identity: 103/379 - (27%)
• Similarity: 184/379 - (48%)
• Gaps: 58/379 - (15%)

  Fly    54 INTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMR 118
            :||.:..|.        :|...|...||:..:.::|.||    :|.|.:||||||:.|.....||
 Worm    26 VNTHEEYED--------IIAEALWPNAVEQWFVYILASM----MVIGVIGNTLVVVVVATNKSMR 78

  Fly   119 TARNLFILNLAISDLLLCLVTMPLTLMEILSK-YWPYGSCSILCKTIAMLQALCIFVSTISITAI 182
            .|.||.::||||:|||:.|..:|||::..::| :|   ..::.||::..:....::||.:|:..|
 Worm    79 NALNLVLMNLAIADLLILLFCLPLTVVNDVTKTFW---FSAVFCKSVNFVNNTSVYVSIMSLVFI 140

  Fly   183 AFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTPALLQQIGLQDTIP- 246
            ..:|::.|.||.:.  .||...:::.|||.:|:.|:||           .|..|...|.....|
 Worm   141 TCERWRAITYPLKS--PFVRTRSVIGGIWFIAMFLSSP-----------EPVTLHLAGAPFVRPN 192

  Fly   247 -------YCIEDWP---SRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKL--KSRITVVAVQA 299
                   .|.|.|.   .:|.:...:|||    :::|:|::|:....:...|  .:....||.:.
 Worm   193 FTTKWGTRCKESWSEEFQKNYQLLQTIFS----FVLPLLVISILCLHMVRTLHFSANYLTVANRQ 253

  Fly   300 SSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNL---YADMERSPVTQSMLVRYAICHMI 361
            .|.::|..|         :|.::..:|.:|.||::.:|:   |..:.....|.::.||..:..:.
 Worm   254 ISIRKKAVR---------MLCAVVFLFSMSNLPVHLYNIALNYDLLSTDVSTNTIAVRKLLPRVF 309

  Fly   362 GMSSACSNPLLYGWLNDNFRKEFQELLCRCSDTNVALNGHTTGCNVQAAARRRR 415
            ..||:|.||:||.:|:..||:||..::|...|...:........::.|:::|.|
 Worm   310 SYSSSCLNPILYSFLSGRFREEFGRVVCCLRDEKSSREFRRKQASLYASSQRVR 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	89/312 (29%)
		TM helix 1	88..114	CDD:320331	12/25 (48%)
		TM helix 2	121..146	CDD:320331	13/24 (54%)
		TM helix 3	161..191	CDD:320331	7/29 (24%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	6/28 (21%)
		TM helix 6	310..340	CDD:320331	6/32 (19%)
		TM helix 7	352..377	CDD:320331	9/24 (38%)
npr-14	NP_001379223.1	7tmA_CCKR-like	48..332	CDD:320124	89/316 (28%)
		TM helix 1	48..74	CDD:320124	12/29 (41%)
		TM helix 2	81..107	CDD:320124	13/25 (52%)
		TM helix 3	119..149	CDD:320124	7/29 (24%)
		TM helix 4	159..177	CDD:320124	7/28 (25%)
		TM helix 5	210..235	CDD:320124	7/28 (25%)
		TM helix 6	255..285	CDD:320124	9/38 (24%)
		TM helix 7	300..325	CDD:320124	9/24 (38%)