Protein Alignment NPFR and npr-33

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_510612.1
• Gene: npr-33 / 185141
• WormBaseID: WBGene00009278
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 365
• Identity: 80/365 - (21%)
• Similarity: 153/365 - (41%)
• Gaps: 67/365 - (18%)

  Fly    92 MYGVLIVFGALGNTLVVIAVIR-KPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYW--P 153
            ::.::|..|.:||..:|..::. :.:|.::.|.|:|||||:||...:...|..::.::.:.|  |
 Worm    65 VFMIIICAGVIGNIFIVFVILMDRKLMSSSVNQFLLNLAIADLGNLIFCSPDAILVLIDRGWLLP 129

  Fly   154 YGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTR-DSLQFVGAVTILAGIWALALLL 217
            ..:|.:|    ..||...::.|.:...||..:|:..|..|.| ........:::|||:|.:|...
 Worm   130 NFACHLL----RFLQEYFLYASVLLQMAIGVERFLAICSPMRMQRFSTKTTISVLAGVWCVAACF 190

  Fly   218 ASPLFVYKELINTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAY- 281
            |||.|:|:.::             ...:.:|.....|...|.|:....|.|.|.:|::.::..|
 Worm   191 ASPYFLYQGIV-------------FHKLYFCFWKGISHKTRTYFKYCELIVLYAIPLVFLTTLYS 242

  Fly   282 ------FGIYNKLKSRITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLN-FFNLY 339
                  :|  |:....|      |:.:|::.....|......|:||:.:.| :.:.|:. .|.|.
 Worm   243 IMCRVLWG--NEDNHNI------ANHSQQEAILKLRRSVVKMLIISMLLYF-LCYTPIQVLFMLE 298

  Fly   340 ADMERSPVTQSMLVRYAICHMIGMSSACSNPLLY----------------------GWLNDNFRK 382
            ..::.|......|  ..:.:::.:.|:.:||::|                      .||..:|.|
 Worm   299 KILDHSVQLPQWL--RLLLNVLSVMSSSTNPIVYIICCRHFRLRLRDVAAGISSFCCWLLPSFSK 361

  Fly   383 EFQELLCRCSDTNVALNGHTTGCNVQAAARRRRKLGAELS 422
            ...|    |.|.::... .:....|...:.||:...|.||
 Worm   362 SEYE----CVDESMTAK-LSRSPYVSFRSSRRQNSRANLS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	71/325 (22%)
		TM helix 1	88..114	CDD:320331	5/22 (23%)
		TM helix 2	121..146	CDD:320331	10/24 (42%)
		TM helix 3	161..191	CDD:320331	6/29 (21%)
		TM helix 4	202..223	CDD:320331	8/20 (40%)
		TM helix 5	258..287	CDD:320331	8/35 (23%)
		TM helix 6	310..340	CDD:320331	8/30 (27%)
		TM helix 7	352..377	CDD:320331	6/46 (13%)
npr-33	NP_510612.1	7tm_classA_rhodopsin-like	62..334	CDD:410626	67/296 (23%)
		TM helix 1	62..87	CDD:410626	5/21 (24%)
		TM helix 2	94..121	CDD:410626	10/26 (38%)
		TM helix 3	133..163	CDD:410626	8/33 (24%)
		TM helix 4	175..194	CDD:410626	7/18 (39%)
		TM helix 5	218..243	CDD:410626	7/24 (29%)
		TM helix 6	268..298	CDD:410626	7/30 (23%)
		TM helix 7	309..334	CDD:410626	5/26 (19%)