Protein Alignment NPFR and npr-16

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001355490.1
• Gene: npr-16 / 180643
• WormBaseID: WBGene00006864
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 78/342 - (22%)
• Similarity: 160/342 - (46%)
• Gaps: 49/342 - (14%)

  Fly    71 LIDRFLSNRAVDSPWYHMLISMYGVLIVFGALG--NTLVVIAVIRKPIMRTARNLFILNLAISDL 133
            :|:...|..|:.....|:.:::....::..|||  |.::::.:|.:|.:|:..|::::.|.::|.
 Worm     1 MINDTYSKHAMSDSSQHLRLALTVTHLLLVALGSVNLIIILLIITRPYLRSITNVYMIGLCLADF 65

  Fly   134 LLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIV------- 191
            :.....:.:....:..|.||:|  ..:|......:|...:.|.:.:..:|.|||..:.
 Worm    66 IYLADLILVAATSLNGKSWPFG--PTICHLFHGTEATGKYASVLFVVLLAADRYIAMCKSDLCGR 128

  Fly   192 YPTRDSLQFVGAVTILAGI-WALALLLASPLFVYKELI--------NTDTPALLQQIGLQDTIPY 247
            |.|..:..|      |:|: |..|.:.:.||:||.:.|        .||:        :::....
 Worm   129 YRTYRTAIF------LSGLAWIAAFICSLPLYVYADEIKVRMRPKNGTDS--------IENNHTL 179

  Fly   248 CIEDWPS-RNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVAVQASSAQRKVERGRR 311
            ||..||| .:.::|.|:.|:.: :::|.|::...|:.::.||:        :|:...|::.|.:|
 Worm   180 CIAHWPSPPHAQWYISVCSVMI-FILPGLVIFYCYYHVFCKLR--------EAAKGSRRLHRNKR 235

  Fly   312 MK----RTNCLLISIAIIFGVSWLPLNFFNLYADMERSPV-TQSMLVRYAICHMIGMSSACSNPL 371
            .:    |....:..:.:...:.|.|...|||::.:.|..: ||.|.:...|.|:....:...||:
 Worm   236 SRSSYQRVTRSVQRVVLFHLLCWSPFWLFNLFSAIFRVRITTQLMRIIVNIIHLFPYVNCALNPV 300

  Fly   372 LYGWLNDNFRKEFQELL 388
            ||.:..:|||..|:.||
 Worm   301 LYAYRAENFRTAFKSLL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	71/319 (22%)
		TM helix 1	88..114	CDD:320331	5/27 (19%)
		TM helix 2	121..146	CDD:320331	3/24 (13%)
		TM helix 3	161..191	CDD:320331	7/29 (24%)
		TM helix 4	202..223	CDD:320331	6/21 (29%)
		TM helix 5	258..287	CDD:320331	6/28 (21%)
		TM helix 6	310..340	CDD:320331	7/33 (21%)
		TM helix 7	352..377	CDD:320331	6/24 (25%)
npr-16	NP_001355490.1	7tm_classA_rhodopsin-like	45..305	CDD:410626	63/284 (22%)
		TM helix 2	53..79	CDD:410626	3/25 (12%)
		TM helix 3	91..121	CDD:410626	7/29 (24%)
		TM helix 4	134..153	CDD:410626	5/24 (21%)
		TM helix 5	190..215	CDD:410626	6/25 (24%)
		TM helix 6	238..268	CDD:410626	6/29 (21%)
		TM helix 7	281..305	CDD:410626	6/23 (26%)