Protein Alignment NPFR and XB994602

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002940541.3
• Gene: XB994602 / 100497124
• XenbaseID: XB-GENE-994603
• Length: 364
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 92/339 - (27%)
• Similarity: 165/339 - (48%)
• Gaps: 40/339 - (11%)

  Fly    88 MLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEIL-SKY 151
            :.|.:|.:|:....|||..:::.:.....:....|..|.|||::||::|:..:|||..... ::.
 Frog    33 LFIPIYALLVTVACLGNCALILLIALTKKLHNTTNFLIGNLALADLVMCIFCVPLTASYAFENRG 97

  Fly   152 WPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALL 216
            |.:|  ..:|..:.::||..:.||.:|:||||.|||.|:|||.|..:.....:.|::.:|.:::.
 Frog    98 WLFG--EFMCHFVTLMQAATVCVSVLSLTAIAVDRYVVVVYPIRRRIGCRSCIYIVSLVWLVSIG 160

  Fly   217 LASPLFVYKELINTDTPALLQQIGLQDTIPYCIEDWPSR-NGRFYYSIFSLCVQYLVPILIVSVA 280
            ::.|.|.:...::      |:..| .|.| .|.|.|.:: ..|..||...|.:.|::|:..::::
 Frog   161 ISMPTFFHTHYLD------LKSAG-HDMI-ICEEFWRNQEKQRLLYSCSLLLLYYMLPLSAITIS 217

  Fly   281 YFGIYNKLKSRITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADMERS 345
            |..|...|:.|    .|..:::..:.:..::.::|..:|....:.||:.||||...||..|::.
 Frog   218 YCAIAYHLRKR----NVPGATSHNQDKWSKKKQKTFRMLSISVMAFGICWLPLQILNLIRDIDE- 277

  Fly   346 PVTQSMLVRYAI------------CHMIGMSSACSNPLLYGWLNDNFRKEFQELLC---RCSDTN 395
                    .:||            ||:|.|||||.||.:|..|:|.||...:....   |.::|.
 Frog   278 --------EFAILDKNYINVIQVTCHLIAMSSACYNPFIYASLHDKFRFHLRNYFFHHKRRANTM 334

  Fly   396 VALNGHTTGCNVQA 409
            ...|.....|:..|
 Frog   335 STKNSRHNTCSTLA 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	87/309 (28%)
		TM helix 1	88..114	CDD:320331	6/25 (24%)
		TM helix 2	121..146	CDD:320331	11/24 (46%)
		TM helix 3	161..191	CDD:320331	14/29 (48%)
		TM helix 4	202..223	CDD:320331	3/20 (15%)
		TM helix 5	258..287	CDD:320331	8/28 (29%)
		TM helix 6	310..340	CDD:320331	10/29 (34%)
		TM helix 7	352..377	CDD:320331	13/36 (36%)
XB994602	XP_002940541.3	7tm_GPCRs	32..320	CDD:475119	87/309 (28%)
		TM helix 1	34..58	CDD:320516	6/23 (26%)
		TM helix 2	67..89	CDD:320516	10/21 (48%)
		TM helix 3	106..128	CDD:320516	8/21 (38%)
		TM helix 4	149..165	CDD:320516	2/15 (13%)
		TM helix 5	196..219	CDD:320516	5/22 (23%)
		TM helix 6	249..271	CDD:320516	7/21 (33%)
		TM helix 7	288..313	CDD:320516	11/24 (46%)