DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NPFR and npy2rl

DIOPT Version :9

Sequence 1:	NP_001246947.1	Gene:	NPFR / 40754	FlyBaseID:	FBgn0037408	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	XP_017948295.1	Gene:	npy2rl / 100494553	XenbaseID:	XB-GENE-922375	Length:	372	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	117/372 - (31%)
Similarity:	184/372 - (49%)	Gaps:	37/372 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LGTVHALNTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHM------LISMYGVLIVFGA 101
            :||:...|.|       .|.|||.|....:..|.....:...:..:      ||:.|.::|:.|.
Frog     1 MGTLKQTNPT-------EELGSRGLHSKSMHTFHGAHTIMMDYTKLVGVQVILIAAYSLIILLGL 58

  Fly   102 LGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAM 166
            :||:||:..:::...|||..|.||.||||:||::....:|.||:..|...|.:|  |:||.....
Frog    59 VGNSLVIYMIVKYKNMRTVTNFFIANLAIADLMVDSFCLPFTLVYTLMDEWKFG--SVLCHLFPY 121

  Fly   167 LQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTD 231
            .||:.:.|||:::..||.|||..||:.....:....:..|::..|..|.:||.||.|::|....|
Frog   122 AQAMSVNVSTLTLIVIALDRYWCIVFHLNSRISKNLSFLIISITWITAAILAIPLAVFREFRYED 186

  Fly   232 TPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVA 296
            .|....:|.:      |.|:|.:|:... ||:..|.:||.:|:.::..||..|:.|||:.|
Frog   187 LPPFNLKIAV------CAENWTNRDSTI-YSLSMLILQYALPLAVICYAYLRIWFKLKNHI---- 240

  Fly   297 VQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADMERSPVTQSMLVRYAICHMI 361
                |...:.|..:|.|.|..:|:.:.::|.|.|||.:.|.|..|:|.:.......:.|.|.|::
Frog   241 ----SPTTRSESQQRRKNTTKMLVMMVVVFAVCWLPFHIFQLAIDLEWTVAIHENKLLYTIFHVV 301

  Fly   362 GMSSACSNPLLYGWLNDNFRKEFQELLCRCSDT------NVALNGHT 402
            .|.|...||.||||:|.|:|..|.... .|.||      :.:|.||:
Frog   302 AMCSTFVNPFLYGWMNKNYRHGFLTFF-GCKDTLQNSQPDGSLRGHS 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tm_4	98..>195	CDD:304433	38/96 (40%)
NPFR	NP_001246947.1	7tm_1	103..373	CDD:278431	88/269 (33%)
npy2rl	XP_017948295.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3897
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940