Protein Alignment NPFR and brs3

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002932668.2
• Gene: brs3 / 100488712
• XenbaseID: XB-GENE-960289
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 411
• Identity: 113/411 - (27%)
• Similarity: 192/411 - (46%)
• Gaps: 42/411 - (10%)

  Fly    37 PLDYLDLGTVHALNTTAINTSDLN-ETGSRPLDPVLIDRFLSNRAVD-SPWYHMLISM---YGVL 96
            |..||:|.  ..|::...||:.|. ..||        |......:.| ||...:|.::   |.|:
 Frog     2 PEGYLNLN--ETLSSVTKNTAHLRFSNGS--------DALYQEESADLSPRLEVLATISITYAVI 56

  Fly    97 IVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILC 161
            |..|.||||:::....:...|:|..|:||.:||..||||.|..:|:.....:...|.:|...  |
 Frog    57 ISVGLLGNTILIKVFFKVKSMQTVPNIFITSLAFGDLLLLLTCVPVDASRYMVDTWLFGRMG--C 119

  Fly   162 KTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAG----IWALALLLASPLF 222
            |.::.:|...:.||..::|.::.|||:.||.|.  .||...||....|    :|.:::|||:|..
 Frog   120 KILSFIQLTSVGVSVFTLTVLSADRYRAIVKPL--ELQTSDAVLKTCGKAACVWIISMLLAAPEA 182

  Fly   223 VYKELINTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNK 287
            |:.:|....:|.  :....:...||.:.:   :..:..:|:....|.|:||:.|:|..|..|...
 Frog   183 VFSDLYEFSSPD--KNTSFKACAPYPVSE---KLMQETHSLMCFLVFYIVPLSIISAYYILIAKT 242

  Fly   288 L-KSRITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYADME-RSPVTQS 350
            | ||...:.|.:.:.|::::|..:|:.:|..:|::   :|...|||.:...||.... .|.|..|
 Frog   243 LYKSTFNMPAEEHTHARKQIESRKRVAKTVLVLVA---LFAFCWLPNHILYLYRSFTYHSAVNSS 304

  Fly   351 MLVRYA--ICHMIGMSSACSNPLLYGWLNDNFRKEFQELLCRC------SDTNVALNGHTTGCNV 407
            ||...|  ...::..|::|.||....||:.:||:.|::.:..|      |..:...:..|||...
 Frog   305 MLHLSATIFARILAFSNSCVNPFALYWLSRSFRQHFKKQVYCCPEQPLQSQPSPTHSSTTTGIAA 369

  Fly   408 QAAARRRRKLGAELSKG-ELK 427
            .....:..::...|..| |:|
 Frog   370 TKGNMQMSEISFTLLSGYEIK 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	89/306 (29%)
		TM helix 1	88..114	CDD:320331	9/28 (32%)
		TM helix 2	121..146	CDD:320331	11/24 (46%)
		TM helix 3	161..191	CDD:320331	9/29 (31%)
		TM helix 4	202..223	CDD:320331	8/24 (33%)
		TM helix 5	258..287	CDD:320331	9/28 (32%)
		TM helix 6	310..340	CDD:320331	8/29 (28%)
		TM helix 7	352..377	CDD:320331	7/26 (27%)
brs3	XP_002932668.2	7tm_GPCRs	47..340	CDD:475119	88/304 (29%)
		TM helix 1	49..73	CDD:410628	8/23 (35%)
		TM helix 2	82..104	CDD:410628	11/21 (52%)
		TM helix 3	120..142	CDD:410628	5/21 (24%)
		TM helix 4	165..181	CDD:410628	5/15 (33%)
		TM helix 5	214..237	CDD:410628	7/22 (32%)
		TM helix 6	269..291	CDD:410628	6/24 (25%)
		TM helix 7	308..333	CDD:410628	6/24 (25%)